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2007, Number 2

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Rev Educ Bioquimica 2007; 26 (2)

Las metalotioneinas y el estrés quirurgico

Scott LEH

Language: Spanish
References: 15
Page: 67-72
PDF size: 160.32 Kb.


ABSTRACT

Metallothioneins (MTs) are a family of low-molecularweight proteins (6-7 KDa). These proteins can bind essential or no essentials metals. The MT are characterized by high contents of sulfhidric groups of cysteine residues that constitute the 33% of the total molecule. In vitro studies show how these proteins are synthesized after a wide variety of chemical and physiological factors like cytokines, hormones, oxygen reactive species, metals and most importantly: stress. Recent studies suggest that Mts are involved in inflammatory response, specially during acute-phase response, even though its specific function in this process has not yet been described.


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