medigraphic.com

2011, Number 2

Rev Med MD 2011; 2.3 (2)

Visceral Leishmaniasis and Mycobacterium tuberculosis in a patient with AIDS in Mexico

Manríquez-Reyes M, Chable-Montero F, Gamboa-Domínguez A, Estradas-Trujillo JA, Chávez-Mazari B, Ingerborg B, Pérez-Patrigeon S, Ponce De León-Garduño A

Language: Spanish
References: 12
Page: 104-107
PDF size: 553.72 Kb.


ABSTRACT

21-years-old man with untreated HIV infection diagnosed 5 years ago and a history of chronic diarrhea and fever. After the initiation of antiretroviral therapy, he presented acute abdomen. Therefore, a laparotomy was performed and in the anatopathologic examination of resected bowel was observed acid-fast bacilli and intracellular infectious structures of Leishmania. He was treated with Amphotericin B, desoxicolate and anti-tuberculosis treatment. Visceral Leishmaniasis is transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. HIV pandemic has changed the natural history of Leishmaniasis, increasing the risk of visceral Leishmaniasis, with an incidence of 1/100-1000 patients in endemic areas. In HIV patients, Leishmania accelerates the AIDS onset, because of the immunosuppression and the stimulation for the virus replication. According to the World Health Organization (WHO), not a case of Visceral Leishmaniasis coinfection and HIV has been reported in Mexico.


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