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2012, Number 3

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Arch Neurocien 2012; 17 (3)

Bipolar disorder and endocrine comorbidity: manic episode associated with hyperprolactinemia. Clinical case report and review of literature

Garfias-García S, Arroyo-Rodríguez S, Durán-del Rivero R
Full text How to cite this article

Language: Spanish
References: 23
Page: 188-194
PDF size: 85.78 Kb.


Key words:

Bipolar disorder, comorbidity, manic episode, hyperprolactinemia.

ABSTRACT

Bipolar disorder coexists with other psychiatric diagnoses and medical comorbidities. The objective of this case report and selective review of the literature is to divulge the comorbidity in bipolar disorder manic episode with psychotic features with a chronic hyperprolactinemic state. We report a female patient 30 years of age with galactorrhea of 6 years of evolution before the onset of any psychiatric treatment. During the study period had two manic episodes with psychotic features, requiring hospitalization on both occasions. Her symptoms subsided in 9 days with treatment with haloperidol and magnesium valproate. We discuss the treatment used and the indication of a second-generation antipsychotic effective in bipolar disorder profile and more appropriate to the circumstances of the case, including the finding of chronic hyperprolactinemia, which after ruled out as causes pituitary adenoma and hypothyroidism, was associated with other findings: polycystic ovaries. Finally, we analyze the probable participation of hyperprolactinemia as a trigger a manic episode.


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Arch Neurocien. 2012;17