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2012, Number 2

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Rev Med MD 2012; 3.4 (2)

Donovanosis Granuloma Inguinale, no Preceding Risk Factors. Case Report

Yanowsky-Reyes G, Pérez-Liñán JA, Aguirre-Jauregui ÓM, Monroy-Martin Y, Camacho-Muñóz E, Santana-Ortiz R
Full text How to cite this article

Language: Spanish
References: 10
Page: 143-145
PDF size: 517.96 Kb.


Key words:

donovanosis, Donovania granulomatis, Calymmatobacterium granulomatis, sexually transmitted diseases.

ABSTRACT

We present the case of a 13 year old male patient who developed a tumor of 12 month duration in penile area over the balanopreputial sulcus. The patient initially presented no pain, but a month ago pain, bleeding, inguinal ganglionic swelling and fetid smell developed without the patient being sexually active. The lesion is 1.5 x 1 cm wide with regular borders, painful to touch base with a purulent fibrin membrane and a fetid smell. Blood count showed leukocytosis, VDRL was negative, urine analyses showed leukocyturia. Patient received antibiotic treatment and afterwards wide margin resection of the tumor. Six month follow up with no disease reappearance. Mexican reports and literature state that this is a rare diagnosis in our country, even in adult patients. In spite that in thi case no sexual contact was documented, when facing genital palpable tumors, donovanosis and other venereal diseases should be considered.


REFERENCES

  1. Medina R. Consideraciones sobre Granuloma Venéreo 130 casos, Instituto Nacional de Venerología, Cátedra de Medicina Tropical Universidad de Caracas; DV -1964-65

  2. Goldberg J. Studies on Granuloma Inguinale V. Isolation of Bacterium Resembling from the faeces of a patient with Granuloma Inguinale. Brit J Vener Dis 1962, vol 38 pp 99-102

  3. O Farrell N. Donovanosis. Sex transm infect 2002; 78(6): 452-7

  4. Carter JS, Bowden FJ, Bastian I, Myers GM, Sriprakash KS, Kemp DJ. Phylogenetic evidence for reclassification of Calymmatobacterium granulomatis as Klebsiella granulomatis comb. nov. Int J Syst Bacteriol. 1999 Oct;49 Pt 4:1695-700

  5. Kharsany AB, Hoosen AA, Kiepiela P, Kirby R, Sturm AW. Phylogenetic analysis of Calymmatobacterium granulomatis based on 16S rRNA gene sequences. J Med Microbiol. 1999 Sep;48(9):841-7

  6. Ted Rosen et al Antibiotic use in sexually transmisible diseases, Dermatol clin 27 (2009) 49 – 61

  7. Brennand GLP, Santana EM, Jardim ML. Cultivation of Calymmatobacterium granulomatis in ouse peritoneal macrophage monolayer. An Bras Dermatol 1999; 74 (3):357-358

  8. Larrondo-Muguercia RJ, Hernández-García LM, González-Angulo AR, Larrondo-La Madrid RP. Lesiones en los genitales externos. Enfoque diagnóstico y conducta que debe seguir el médico de la familia, Rev Cubana Med Gen Integr 1998;14(1)

  9. Centro Nacional de Vigilancia Epidemiológica y Control de Enfermedades CENAVECE. Boletín epidemiológico 2012: semana epidemiológica núm. 43 del 21 al 27 de octubre de 2012. Accesado el: 05 de noviembre de 2012. Disponible en: http://www.dgepi.salud.gob.mx/2010/plantilla/i ntd_boletin.html

  10. Bowden FJ, Mein J, Plunkett C, et al. Pilot study of azithromycin in the treatment of genital donovanosis. Genitouri Med 1994; 72(1):17-19




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Rev Med MD. 2012;3.4