2012, Number 2
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ABSTRACTBackground: It is estimated that 15% of couples living in industrialized countries are infertile (have failed to conceive during reproductive age, after 12 months or more of regular intercourse without contraception). During the past decade the demand for assisted reproductive technology (ART) treatments has increased due to its greater efficacy.
Objective: To unify criteria regarding the therapeutic approach and service to patients and to set a precedent for the creation of a Mexican Official Regulation with respect to these topics, and to further support in the legislation of these procedures.
Method: Consensus by a group panel of experts with the participation of 34 national accredited ART centers. Seven workshops were organized with the following topics: 1) selection of patients for ART treatment, 2) controlled ovarian stimulation protocols for high complexity ART treatment, 3) preparation and egg retrieval technique, 4) embryo transfer; 5) luteal phase supplementation; 6) indications and techniques of cryopreservation and 7) informed consent. Each workshop was integrated by a coordinator who described and presented the conclusions to the expert panel. The expert panel then pointed out a series of observations until unanimous criteria was reached, which are reflected in this document.
Results: Patient selection for ART is the first step of the process. Proper patient selection leads to success, in the same way that a bad selection leads to failure. In the case of egg donation, the most important recommendation is that only one to two embryos be transferred, in order to reduce multiple pregnancies while maintaining high pregnancy rates.
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Beckers NG, Macklon NS, Eijkemans MJ, Ludwig M, et al. Nonsupplemented luteal phase characteristics after the administration of recombinant human chorionic gonadotropin, recombinant luteinizing hormone, or gonadotropinreleasing hormone (GnRH) agonist to induce final oocyte maturation in in vitro fertilization patients after ovarian stimulation with recombinant follicle-stimulating hormone and GnRH antagonist cotreatment. J Clin Endocrinol Metab 2003;88:4186-4192.