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Antes Revista del Instituto Nacional de Enfermedades Respiratorias

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2012, Number 4

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Neumol Cir Torax 2012; 71 (4)

Wood smoke as a risk factor for lung cancer in nonsmoking hospitalized population

García-Sancho FC, Fernández-Plata R, Rivera-de la Garza MS, Mora-Pizano MA, Martínez-Briseño D, Franco-Marina F, Pérez-Padilla JR

Language: Spanish
References: 34
Page: 325-332
PDF size: 124.31 Kb.


ABSTRACT

Objective: Our objective was to identify risk factors in hospitalized patients with lung cancer treated at a national referral hospital for respiratory diseases. Material and methods: We analyzed routinely obtained occupational, environmental and household exposures and hospitalization databases in a retrospective case-control study. The clinical charts of adult HIV-negative patients (≥18 years old), were examined (from 1999-2009). The five groups of patients (cases) were: 1) 1,067 patients with lung cancer (all of them); 2) 826 patients with adenocarcinoma; 3) 152 patients with squamous cell lung cancer; 4) 51 patients with small-cell lung cancer, and 5) 38 patients with large-cell lung cancer all biopsy proven. The controls were otolaryngology patients without lung diseases and age › 30 years old (n = 797). All of cases were nonsmokers and both sexes. We analyzed also these groups of patients by gender, in nonsmoking women. Institutional committees approved protocol. Results: Cases were older with high prevalence of exposure to wood smoke than controls. In the multivariate analysis, after controlling for potential confounders, past or current exposure to wood smoke was associated with: lung cancer (OR = 2.0 [95% CI 1.6-2.6] p ‹ 0.0001); adenocarcinoma (OR = 2.1 [95% CI 1.6-2.7] p ‹ 0.0001); squamous cell lung cancer (OR = 1.6 [95% CI 1.03-2.5] p = 0.03); small cell lung cancer (OR = 2.2 [95% CI 1.1-4.3] p = 0.02) and large cells lung cancer (OR = 1.8 [95% CI 0.9-3.7] p = 0.1); in the same models, passive smoking was not significantly associated with lung cancer. In nonsmoking women, similar results were observed. Conclusions: Exposure to wood smoke was associated with lung cancer in non-smoking men and woman.


REFERENCES

  1. Torres-Duque C, Maldonado D, Pérez-Padilla R, Ezzati M, Viegi G; Forum of International Respiratory Studies (FIRS) Task Force on Health Effects of Biomass Exposure. Biomass fuels and respiratory diseases: a review of the evidence. Proc Am Thorac Soc 2008;5:577-590.

  2. Ko Y, Lee CH, Chen MJ, et al. Risk factors for primary lung cancer among non-smoking women in Taiwan. Int J Epidemiol 1997;26:24-31.

  3. Masera OR. Sustainable fuel wood use in rural Mexico. Volume I: Current patterns of resource use. Report No. LBL-34634. CA, US: Energy and Environment Division, Laurence Berkeley Lab., CA; 1993.

  4. Secretaría de Energía (Sener). Balance Nacional de Energía 2001. México, D.F., Sener; 2002.

  5. Díaz JR. Consumo de leña en el sector residencial de México. Evolución histórica y emisiones de CO2 [tesis]. México, D.F.: UNAM; 2000. p.106.

  6. Instituto Nacional de Estadística y Geografía. Censo de Población y Vivienda 2010. Cuestionario básico. Estados Unidos Mexicanos/Vivienda. Fecha de consulta: 6 de diciembre, 2011. Disponible en: http://www3.inegi.org.mx/sistemas/TabuladosBasicos/

  7. Delgado J, Martínez LM, Sánchez TT, Ramírez A, Iturria C, González-Ávila G. Lung cancer pathogenesis associated with wood smoke exposure. Chest 2005;128:124-131.

  8. International Agency for Research on Cancer (IARC). Monographs on the evaluation of carcinogenic risks to humans, volume 95. Household Use of solid fuels and high temperature frying. Lyon, France: IARC; 2010. Available in: http://monographs.iarc.fr/ENG/Monographs/vol95/index.php

  9. Zhang J, Smite KR, Ma Y, et al. Greenhouse gases and other airborne pollutants from household stoves in China: a database for emission factors. Atmospheric Environment 2000;34:4537-4549.

  10. World Health Organization. International Statistical Classification of Diseases and Related Health Problems. 10ª Revisión. Access date: December 06, 2011. Available from: http://apps.who.int/classifications/icd10/browse/2010/

  11. Lim WY, Seow A. Biomass fuels and lung cancer. Respirology 2012;17:20-31. doi: 10.1111/j.1440-1843.2011.02088.x

  12. Chen CJ, Wu HY, Chuang YC, et al. Epidemiologic characteristics and multiple risk factors of lung cancer in Taiwan. Anticancer Res 1990;10:971-976.

  13. Pisani P, Srivatanakul P, Randerson-Moor J, et al. GSTM1 and CYP1A1 polymorphisms, tobacco, air pollution, and lung cancer: a study in rural Thailand. Cancer Epidemiol Biomarkers Prev 2006;15:667-674.

  14. Liu Q, Sasco AJ, Riboli E, Hu MX. Indoor air pollution and lung cancer in Guangzhou, People’s Republic of China. Am J Epidemiol 1993;137:145-154.

  15. Gupta D, Boffetta P, Gaborieau V, Jindal SK. Risk factors of lung cancer in Chandigarh, India. Indian J Med Res 2001;113:142-150.

  16. Tang L, Lim W-Y, Eng P, et al. Lung cancer in Chinese women: evidence for an interaction between tobacco smoking and exposure to inhalants in the indoor environment. Environ Health Perspect 2010;118:1257-1260.

  17. Mzileni O, Sitas F, Steyn K, Carrara H, Bekker P. Lung cancer, tobacco, and environmental factors in the African population of the Northern Province, South Africa. Tob Control 1999;8:398-401.

  18. Le CH, Ko YC, Cheng LS, et al. The heterogeneity in risk factors of lung cancer and the difference of histologic distribution between genders in Taiwan. Cancer Causes Control 2001;12:289-300.

  19. Hernández-Garduño E, Brauer M, Pérez-Neria J, Vedal S. Wood smoke exposure and lung adenocarcinoma in non-smoking Mexican women. Int J Tuberc Lung Dis 2004;8:377-383.

  20. Sobue T. Association of indoor air pollution and lifestyle with lung cancer in Osaka, Japan. Int J Epidemiol 1990;19 (Suppl 1):S62-S66.

  21. Behera D, Balamugesh T. Indoor air pollution as a risk factor for lung cancer in women. J Assoc Physicians India 2005; 53:190-192.

  22. Hosgood HD 3rd, Boffetta P, Greenland S, et al. In-home coal and wood use and lung cancer risk: a pooled analysis of the International Lung Cancer Consortium. Environ Health Perspect 2010;118:1743-1747.

  23. Gao Y-T, Blot WJ, Zheng W, et al. Lung cancer among Chinese women. Int J Cancer 1987;40:604-609.

  24. Koo LC, Lee N, Ho JH. Do cooking fuels pose a risk for lung cancer? A case-control study of women in Hong Kong. Ecol Dis 1983;2:255-265.

  25. Shen XB, Wang GX, Huang YZ, Xiang LS, Wang XH. Analysis and estimates of attributable risk factors for lung cancer in Nanjing, China. Lung Cancer 1996;14 (Suppl 1):S107-S112.

  26. Sapkota A, Gajalakshmi V, Jetly DH, et al. Indoor air pollution from solid fuels and risk of hypopharyngeal/laryngeal and lung cancers: a multicentric case-control study from India. Int J Epidemiol 2008;37:321-328.

  27. Ramanakumar AV, Parent ME, Siemiatycki J. Risk of lung cancer from residential heating and cooking fuels in Montreal, Canada. Am J Epidemiol 2007;165:634-642.

  28. Wu-Williams AH, Dai XD, Blot W, et al. Lung cancer among women in north-east China. Br J Cancer 1990;62:982-987.

  29. Xu Z-Y, Blot WJ, Xiao H-P, et al. Smoking, air pollution, and the high rates of lung cancer in Shenyang, China. J Natl Cancer Inst 1989;81:1800-1806.

  30. Malats N, Camus-Radon AM, Nyberg F, et al. Lung cancer risk in non smokers and GSTM1 and GSTT1 genetic polymorphism. Cancer Epidemiol Biomarkers Prev 2000;9:827-833.

  31. Lissowska J, Bardin-Mikolajczak A, Fletcher T, et al. Lung cancer and indoor pollution from heating and cooking with solid fuels: the IARC international multicentre case-control study in Eastern/Central Europe and the United Kingdom. Am J Epidemiol 2005;162:326-333.

  32. Wang XR, Chiu YL, Qiu H, Au JS, Yu IT. The roles of smoking and cooking emissions in lung cancer risk among Chinese women in Hong Kong. Ann Oncol 2009;20:746-751.

  33. Brauer M, Bartlett K, Regalado-Pineda J, Perez-Padilla R. Assessment of particulate concentrations from domestic biomass combustion in rural Mexico. Environ Sci Technol 1995;30:104-109.

  34. Bruce N, Neufeld L, Boy E, West C. Indoor biofuel air pollution and respiratory health: the role of confounding factors among women in highland Guatemala. Int J Epidemiol 1998;27:454-458.




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