Zaldívar OJR, Rodríguez CA, Quesada CM, Martínez ÁM, Santiago OA, Menéndez RM

Language: Spanish
References: 11
Page: 1948-1953
PDF size: 254.92 Kb.

ABSTRACT

The case of a term infant by dystocia (ces arean section) due to pregnancy toxemia with history of polyhydramnios is presented, who had respiratory distress a few minutes after birth and he was admitted to "Dr. Juan de la Cruz Martínez Maceira" Northern Children Hospital of Santiago de Cuba. Very low blood glucose levels were detected that progressively caused tonic-clonic seizures, which frequencies could not be reduced. He was diagnosed with persistent hyperinsulinem ic hypoglycemia (nesidioblastosis) and was transferred to Havana to receive definitive c linical and surgical tr eatments. Currently, he is treated by a multidisciplinary medical team.

REFERENCES

1. Lee PJ, Leonard JV. Hypoglycemia. En: Brook GD, Clayton P, Brown R. Brook ́s Clinical Pediatric Endocrinology. 3 ed. London: Blackwell Science; 1995. V 35. p. 677-93.

2. Dacou-Voutetakis C, Psychou F, Maniati-Ch ristidis M. Persistent hyperinsulinemic hypoglycemia of infancy: long-term resu lts. J Pediatr Endo crinol Metab. 1998; 11(Suppl 1): 131-41.

3. Sinha S, Kwok-Chun Chan K, Sadeghi-Ne jad A. Hyperinsulinism [citado 30 Dic 2011]. Disponible en: http://www.emed icine.com/PED/topic1075.htm

4. Aynsley-Green A, Hussain K, Hall J, Saudubray JM, Nihoul-Fékété C, De Lonlay- Debeney P, et al. Practical management of hyperinsulinism in infancy. Arch Dis Child Fetal Neonatal Ed. 2000; 82(2): 98-107.

5. James C, Kapoor RR, Ismail D, Hussain K. The genetic basis of congenital hyperinsulinism. J Med Genet. 2009; 46(5): 289-99.

6. Arnoux JB, de Lonlay P, Ribeiro MJ, Hussain K, Blankenstein O, Mohnike K, et al. Congenital hyperinsul inism. Early Hum Dev. 2010; 86(5): 287-94.

7. Magge SN, Shyng SL, MacMullen C, Steinkrauss L, Ganguly A, Katz LE, et al. Familial leucine-sensitive hypoglycemia of infancy du e to a dominant mutation of the beta-cell sulfonylurea receptor. J Clin En docrinol Metab. 2004; 89(9): 4450-6.

8. Flanagan SE, Kapoor RR, Banerjee I, Hall C, Smith W, Hussain K, et al. Dominantly acting ABCC8 mutations in patients with medically unresponsive hyperinsulinaemic hypoglycaemia. Clin Genet. 2011; 79(6): 582-7.

9. Kapoor RR, James C, Flanagan SE, Ellard S, Eaton S, Hussain K. 3-Hydroxyacyl- coenzyme. A dehydrogenase deficiency and hyperinsulinemic hypoglycemia: characterization of a novel mutation and seve re dietary protein sensitivity. J Clin Endocrinol Metab. 2009; 94(7): 2221-5.

10. Lee PJ, Leonard JV. Hypoglycaemia. En: Brook GD. Clinical pediatric endocrinology. 3 ed. London: Blackwell Science; 1995. p. 677-93.

11. Anzoátegui Espínola RE, Dorantes Álvarez LM , García Morales LM, Bracho Blanchet EJ, Garibay Nieto GN, Sadowinski Pine S. Hipo glucemia hiperinsulinémica persistente de la infancia: revisión de casos en un período de 10 ańos. Bol Med Hosp Infant Mex. 2000; 57(7): 383-9.