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Colegio de Medicina Interna de México.

2013, Number 1

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Med Int Mex 2013; 29 (1)

Hemophagocytic syndrome; a case report and review of literature

García NM, Calvo CJE, Duarte MJ, Romero-Figueroa S

Language: Spanish
References: 12
Page: 101-105
PDF size: 162.15 Kb.


ABSTRACT

The Hemophagocytic Syndrome, also referred as Haemophagocityc Lymphohistiocytosis is a clinicopathologic entity characterized by the activation of histocytes with hemophagocytosis in bone marrow and reticuloendothelial system, triggered by default in the T lymphocyte by stimulating the production of INF-γ and multiple interleukins involved that promote macrophage activation, this disease curse with fever, cytopenias, hepatosplenomegaly and hemophagocytosis, know the pathophysiology, identify the condition in a timely manner and early treatment are key factors in patient survival.


REFERENCES

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  2. Henter Jan-Inge, Samuelsson-Horne AC, et al. Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Rev Blood 2002;100:2367-2373.

  3. Kumakura S. Hemophagocytic Syndrome. Intern Med 2005;44:278-280.

  4. Mayordomo-Colunga J, Rey C, González S, Concha A. Multiorgan failure due to hemophagocytic syndrome: A case report. Rev Cases Journal 2008;1:209.

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  8. Fisman ND. Hemophagocytic Syndromes and Infection. Emerg Infect Dis 2000;6:601-608.

  9. Kumakura S, Ishikura H, Kondo M, Murakawa Y, Masuda J, Kobayashi S. Autoimmune-associated hemophagocityc syndrome. Mod Rheumatol 2004;14:205-215.

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  11. Emmeneger U, Reimers A, Frey U, Fux Ch, Bihl F, Semela D, et al. Reactive Macrophage Activation Syndrome: a simple screening strategy and its potential in early treatment initiation. Swiss Med Wkly 2002;132:230-236.

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