Rodríguez FZ, Pierre-Charlot D, Falcón VGC, Mustelier FHL

Language: Spanish
References: 15
Page: 1-9
PDF size: 255.54 Kb.

ABSTRACT

Introduction: Despite advances in used diagnostic tools, the identification of malignant thyroid nodules is still a challe nge for pathologists, endocrinologists and surgeons.
Methods: An observational, descriptive and prospective study was carried out in 204 patients with nodular thyroid disease, treated at outpatient department in “Saturnino Lora” Provincial Teaching Hospital of Santiago de Cuba (2007-2011), in whom cytology by fine-needle aspiration biopsy was performed.
Objective: To determine the diagnostic effectiveness of the cytology with fine-needle aspiration biopsy by comparing it with the result of final histological examination, as well as its economic impact.
Results: The report of the cytology by fine-needle aspiration biopsy was negative for malignancy in 111 patients (54.5 %) and positive in 23 (11.3 %); false positive in 4 (2.0 %), false negative in 20 (9.8 %) and without diagnosis in 40 (19.6 %). Indicators of effectiveness identified were sensitivity (53.5 %), specificity (96.5 %), diagnostic accuracy (65.7 %), and positive and negative predictive values (85.2 and 84.7 %, respectively). There were 1.5% of complications and the average cost of the cytology was 50 times lower than that of thyroid surgery.
Conclusions: Although this method is simple to perform, practically safe and inexpensive, the presence of the cytopathologist during its application is essential to guarantee the appropriate indica tors of effectiveness.

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