Valladares VM, Conde CT, Díaz YNM

Language: Spanish
References: 8
Page: 522-525
PDF size: 119.63 Kb.

ABSTRACT

Paget's disease is a special variety of breast cancer. It is a rare disease that represents 1 to 3% of all breast cancers and is clinically characterized as an eczematous lesion on the nipple, later progressing to the areola surface and terminal lactiferous ducts. We present the case of a 48 years old female patient who attended consultation because of discoloration, eczema and depression of the nipple. Skin retraction and retroareolar palpable tumour were found. Through mammography, asymmetry was observed in the density of right mammary parenchyma in respect to the left retroarelar. It had a tumoural appearance. The biopsy was positive for Paget cells and invasive ductal carcinoma. As rare as this case is, we decided to have it published.

REFERENCES

1. Rodríguez Pérez A. Afecciones mamarias. La Habana: Editorial Ciencias Médicas; 2010.

2. Albarran JM, Tavares A, Saldivia F, Prince J, Ramos S, Gutiérrez N, Gadea C. Enfermedad de Paget de la mama. Reporte de 13 casos. Rev Venez Oncol. 2010;22(3):194-200.

3. Aranibar L, Arellano J, Ramírez C. Enfermedad de Paget, diferentes formas de una misma enfermedad. Piel. 2012;27(4):178-81.

4. Káram Orantes M, Pichardo Velázquez P, Fonte Avalos V, Toussaint Caire S, Ortiz Hidalgo C, Vega Memije E. Enfermedad de Paget mamaria: comunicación de un caso y revisión de la literatura. Gac Méd Méx[revista en Inter net]. 2006[citado 23 Ene 2012];142(3):[aprox. 10 p.]. Disponible en: http://www.scielo.org.mx/scielo.php? script=sci_arttext&pid=S0016-38132006000300011.

5. Instituto Nacional del Cáncer. Enfermedad de Paget del seno[Internet]. Bethesda: Instituto Nacional del Cáncer; 2011[citado 10 Abr 2012]. Disponible en: http://www.cancer.gov/espanol/recursos/hojas-informativas/tipos/paget -seno.

6. Harris JR, Lippman ME, Morrow M, Osborne CK. Diseases of the Breast. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2009.

7. Caliskan M, Gatti G, Sosnovskikh I, Rosmensz NE, Botteri E, Musmeci S, et al. Paget's disease of the breast: the experience of the European Institute of Oncology and review of the literature. Breast Cancer Res Treat. 2008;112(3):513–21.

8. Kanitakis J. Mammary and extramammary Paget's disease. J Eur Acad Dermatol Venereol. 2007;21(5):581-90.