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2012, Number 3

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Rev Cuba Endoc 2012; 23 (3)

Clinical applications of radioiodine 131 (I131) in the thyroid diseases

González RL, Turcios TSE, Velasco MM
Full text How to cite this article

Language: Spanish
References: 13
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Key words:

thyroid disease, radioiodine 131, hyperthyroidism, goiter, thyroid cancer.

ABSTRACT

Radioiodine 131 is a radioactive isotope that is successfully used for the diagnosis and the treatment of benign and malignant thyroid diseases. Its quality of selectively integrating to the thyroid metabolism and emitting a signal allows it to describe the gland functioning through capture studies, and to delimit the morphology and location of the tissues that capture iodine by means of gammagraphy. It is also a simple, safe and cost-effective radiotherapy used as first-line therapeutics in the control of hyperthyroidism. The dose and right time of application should be individualized according to the etiology and the clinic of each patient. Radioiodine 131 offers an efficient alternative to reduce the size of non-toxic goiter in addition to supporting the surgical treatment of the differentiated thyroid carcinoma and destroying with ablative doses the tissular remains and the metastatic lesions that can be detected during the gammagraphic follow-up. Radioiodine 131 depends on the fulfillment of safety regulations against radioactivity.


REFERENCES

  1. Velasco M, Martínez A. Diagnóstico y terapéutica con 131I en afecciones tiroideas. Rev Cubana Endocrinol [serie en Internet]. 2004 [citado 29 de febrero de 2012];15(1). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-29532004000100009&lng=es&nrm=iso&tlng=es

  2. Graham GD, Burman KD. Radioiodine treatment of Graves' disease. An assessment of its potential risks. Ann Intern Med. 1986;105:900-5.

  3. Franklyn JA, Boelaert K. Thyrotoxicosis. Lancet. 2012;379(9821):1155-66.

  4. American Thyroid Association Taskforce on Radioiodine Safety, Sisson JC, Freitas J, McDougall IR, Dauer LT, Hurley JR, et al. Radiation safety in the treatment of patients with thyroid diseases by radioiodine 131I: practice recommendations of the American Thyroid Association. Thyroid. 2011;21(4):335-46.

  5. Turcios SE, Yanes M, Cruz J, Rodríguez JC. Actualización de la conducta diagnóstica en el nódulo de tiroides. Rev Cubana Endocrinol [serie en Internet]. 2010 [citado 13 de noviembre de 2012];21(3). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-29532010000300007&lng=es&nrm=iso

  6. Bahn Chair RS, Burch HB, Cooper DS, Garber JR, Greenlee MC, Klein I, et al. Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists. Thyroid. 2011;21(6):593-646.

  7. Navarro DA. Uso del yodo radiactivo: lo nuevo y lo viejo. Rev Cubana Endocrinol [serie en Internet]. 2004 [citado 22 de abril de 2012];15(3). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-29532004000300001&lng=es&nrm=iso

  8. Ochoa F, Knight HG, Alavez E. Tratamiento del bocio tóxico difuso con 131I en dosis de 80 µCi/g de tejido tiroideo. Rev Cubana Endocrinol [serie en Internet]. 2004 [citado 29 de febrero de 2012];15(3). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-29532004000300006&lng=es&nrm=iso

  9. Santos RB, Romaldini JH, Ward LS. A randomized controlled trial to evaluate the effectiveness of 2 regimens of fixed iodine (131I) doses for Graves' disease treatment. Clin Nucl Med. 2012 Mar;37(3):241-4.

  10. Bartalena L. The dilemma of how to manage Graves' disease in patients with associated orbitopathy. J Clin Endocrinol Metab. 2011;96(3):592-9.

  11. Bonnema SJ, Nielsen VE, Hegedus L. Long-term effects of radioiodine on thyroid function, size and patient satisfaction in non-toxic diffuse goitre. Eur J Endocrinol. 2004;150(4):439-45.

  12. Haugen BR. Radioiodine remnant ablation: current indications and dosing regimens. Endocr Pract. 2012;18(4):604-10.

  13. Schlumberger M, Catargi B, Borget I, Deandreis D, Zerdoud S, Bridji B, et al. Strategies of radioiodine ablation in patients with low-risk thyroid cancer. N Engl J Med. 2012;366(18):1663-73.




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Rev Cuba Endoc. 2012;23