2012, Number 6
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Rev ADM 2012; 69 (6)
Frequency of Sjögren's Syndrome in patients with hiposalivación
Ibáñez MNG, Piña LYB, López GCJ
Language: Spanish
References: 16
Page: 282-286
PDF size: 145.58 Kb.
ABSTRACT
Sjögren's Syndrome (SS) is a multisystem autoimmune
disease that results from the destruction of the
exocrine glands. Its prevalence is between 0.05 and
4.8% of the population and it is more common in
women. Oral complications include traumatic ulcers,
cervical caries, issues with prosthesis use, and
candidiasis, all of these associated with dry mouth. The
diagnosis of Sjögren's Syndrome should be based on
international criteria. Its treatment is multidisciplinary;
it is essential that hyposalivation be managed in order
to avoid secondary alterations.
Objetive: To determine the frequency of Sjögren's
Syndrome in patients with dry mouth.
Methods: A descriptive, cross-sectional, observational
study was performed using a sample consisting of 23
cases. Information relating to age, sex, and Sjogren's
Syndrome diagnosis criteria was gathered using a data
collection sheet. Testing was carried out to determine
the independence of the variables.
Results: The sample represented 4.6% of all patients.
The male-to-female ratio was 1:6.6, in an age range
from 40 to 81 years;14 patients suffered from
xerophthalmia, of whom 86% were women (p ‹0.05);
16 patients suffered from xerostomia, of whom 87%
(14 patients) were women (p ‹0.05). 6 cases of SS were
diagnosed, with a male-to-female ratio of 1:5.
Discussion: 26% of patients fulfilled 4 or 5 of the
criteria for the diagnosis of Sjögren's Syndrome. Once
the criteria for its diagnosis have been shown to exist, it
is possible for the dentist to produce a diagnosis of SS,
following a basic protocol of symptom recording, the
observation of signs, and complementary testing.
Conclusions: Sjögren's Syndrome is an autoimmune
disease characterized by dry mouth. For it to be
diagnosed, a biopsy of minor salivary glands of the lip
is required in search of benign lymphoepithelial
lesions, the presence of which is a reliable criterion for
the diagnosis of this disease.
REFERENCES
Barrille-Fabris. Sindrome de Sjögren. Rev Mex Reumat 2004;18(2):137-46.
Mosqueda Taylor A ,et al. Tópicos selectos de Oncología Bucal. Planeación y desarrollo editorial. México, D.F. 2007.
Bagán JV. Medicina Bucal. Editorial Medicina Oral, S.L. 2da Edicion. Valencia España 2010.
Neville, Damm, Allen, Bouquot. Oral & Maxillofacial Pathology. 3ra Edición. U.S.A. WB Saunders; 2009.
Ibáñez NR. Hiposalivación/Xerostomía. Med Oral 2011;2:58-64.
Mathews, Kurien and Scofield. Oral Manifestations of Sjögren's Syndrome. Criterial reviews. Oral Biology & Medicine 2008;87(4):308-18.
Margaix M, Bagan JV, Proveda R, Jumenez Y and Carrión G. Sjögren's Syndrome of the oral cavity. Review and Update. Med Oral Patol Oral Cir Bucal 2009;14(7):325-30.
Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL et al. Classification criteria for Sjögren's syndrome: a revised version of the Erupean criteria proposed by the American- European Consensus Group. Ann Rheum Dis 2002;61:554-8.
Wong David T. Salivary Diagnostics. Wiley-Blackwell, U.S. 2008.
Bültzingslöwen I,Sollecito T, Fox P, Daniels T, Jonsson R et al. Salivary dysfunction associated with systemic diseases: systematic review and clinical management recommendations. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103(suppl 1):S57.e1-S57.e15.
Porter SR., Scully C., Path FRC., Hegarty AM. An update of the etiology and management of xerostomia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;97:28-46.
Fox P., Browman J., Segal B and cols. Oral involvement in primary Sjögren syndrome. J Am Dent Assoc 2008;139:1592- 1601.
Pacholke H, Amdur R, Morris C, Li J, Dempsey J, Hinerman R, Mendenhall W. Late Xerostomia After Intensity-Modulated Radiation Therapy Versus Conventional Radiotherapy. Am J Clin Oncol 2005; 28: 351-8.
Scardina GA, Sapano G. Carini. Diagnostic Evaluation of Serial sections of Labial Salivary Gland Biopsies in Sjögren's Syndrome. Med Oral Patol Oral Cir Bucal 2007;12(8):565-8.
Bascones A, Tenovuo J, Ship J, Turner M, Mac – Veigh I, López-Ibor JM, Lanzos E, Aliaga A. Conclusiones del Simposium 2007 de la Sociedad Española de Medicina Oral sobre “Xerostomía. Síndrome de Boca Seca. Boca Ardiente”. Av Odontoestomatol 2007; 23 (3): 119-126.
López P, Bermejo A, Bagan JV, Pascual E. Comparison of a New Test for the Measurement of Resting Whole Saliva with the Training and the Swali Techniques. Braz Dent J 1996;7:81-86.