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Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

2012, Number 6

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Rev Invest Clin 2012; 64 (6)

Features of hospital-acquired infections in newborns with culture-positive

Tapia-Rombo CA, Díaz-Cantinca I, Uscanga-Carrasco H, Tena-Reyes D

Language: Spanish
References: 30
Page: 508-520
PDF size: 239.62 Kb.


ABSTRACT

Objective. To determine the prevalence of nosocomial infection (NI) in newborns (NB) as well as the etiology, frequency mortality related to these infections in a tertiary-care hospital. Material and methods. A retrospective epidemiological study was carried out with NB admitted to a tertiary-care neonatology hospital service from January 2006 to December 2008 who complied with selection criteria. All NB between the gestational ages of 25 to 44 weeks, NI supported by positive culture and either local or systemic infection were included. Descriptive statistic was used. Results. NI prevalence in the Neonatal Service was an average of 30.4%. The most common microorganisms isolated in first event cultures (n = 100) were Gram-positive bacteria such as coagulase- negative staphylococci found in 55 patients (55%), followed by Gram-negative bacteria present in 44 patients (44%) and fungi such as Candida albicans and Candida sp. from 8 patients (8 %); as to the second event (n = 32), Gramnegative bacteria were isolated from 20 patients (62.5%), Gram-positive bacteria such as coagulase-negative staphylococci were present in 6 patients (18.7%) and fungi such as Candida albicans were found in 5 patients (15.6%). Finally, regarding the third event (n = 18), Gram-negative bacteria were present in 16 patients (88.9%), Gram-positive bacteria were found in 15 patients (83.3%) such as coagulase-negative staphylococci in 10 patients (55.5%), and fungi such as Candida sp. in two (11.1%). Twelve (12%) who died secondary to IN, two suffered three NI events. Conclusions. Awareness of the various characteristics of NI in the work area (etiology, prevalence, and final outcome) is of great importance to design new interventions.


REFERENCES

  1. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988; 16: 128-40.

  2. Pooli L, Nocetti FM, De Califano GM, Rial MJ, Martín MT. Incidencia de infección hospitalaria y factores de riesgo asociados en una Unidad de Cuidados Intensivos Neonatales. Disponible en: http://www.elizalde.gov.ar/area_medica/Revista/ vol12002

  3. Mendívil C, Egües J, Polo P, Ollaquindia P, Nuin MA, Del Real C. Infección nosocomial, vigilancia y control de la infección en neonatología. Anales Sin San Navarra 2000; 23(Supl. 2): 177-84.

  4. Alda SM. Prevención de infecciones hospitalarias en las unidades de cuidado intensivo neonatal (UCIN). Rev Hosp Mat Inf Ramón Sardá 2004; 24: l48-58.

  5. Castro FW, González HG, Alfonso MJE. Cuidados de enfermería para la prevención de las infecciones postnatales. Rev Cubana Enfermer 2005; 21: 1-8.

  6. Ramírez DJ. Sepsis neonatal bacteriana. Rev Perinatol 1999; 14: 19-32.

  7. Heeg P. Infecciones nosocomiales en neonatología y unidades de cuidado intensivo neonatales (UCIN). Infect Control 2006; 2: 82-6.

  8. Orfali JL. Sepsis Neonatal. Nuevas estrategias terapéuticas. Rev Ped Elec 2004; 1: 25-31.

  9. González MA, Caraballo MA, Guerrero SA, Montenegro SO. Sepsis neonatal y prematurez. Revista de Posgrado de la Vía Cátedra de Medicina 2006; 160: 22-8.

  10. Zamora-Castorena S, Murguía-de-Sierra MT. Cinco años de experiencia con sepsis neonatal en un centro pediátrico. Rev Invest Clin 1998; 50: 463-70.

  11. Stoll BJ, Hansen N. Infections in VLBW infants: studies from the NICHD Neonatal Research Network. Semin Perinatol 2003; 27: 293-301.

  12. Makhoul IR, Sujov P, Smolkin T, Lusky A, Reichman B. Epidemiological, clinical and microbiological characteristics of late-onset sepsis among very low birth weight infants in Israel: a national survey. Pediatrics 2002; 109: 34-9.

  13. Tapia-Rombo CA, Ugarte-Torres RG, Álvarez-Vázquez E, Salazar- Acuña AH. Risk factors for intrahospital infection in newborns. Arch Med Res 2001; 32: 304-11.

  14. Rodríguez-Weber MA, López-Candiani C, Arredondo-García JL, Gutiérrez-Castrellón P, Sánchez-Arriaga F. Morbilidad y mortalidad por sepsis neonatal en un hospital de tercer nivel de atención. Sal Pub Mex 2003; 45: 90-5.

  15. Tapia-Rombo CA, Cortés-Sauza J, Saucedo-Zavala VJ, Cuevas- Urióstegui ML. Posibles factores de riesgo que influyen en la mortalidad por sepsis neonatal. Gac Med Mex 2006; 142: 283-9.

  16. Rodríguez CJ, Fraga JM, García RC, Fernández LJR, Martínez SI. Sepsis neonatal: indicadores epidemiológicos en relación con el peso del recién nacido y el tiempo de hospitalización. An Esp Pediatr 1998; 48: 401-08.

  17. Stoll BJ, Gordon T, Korones SB, Shankaram S, Tyson JE, Bauer CR, et al. Early-onset sepsis in very low birth weight neonates: a report from the National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr 1996; 129: 72-80.

  18. Stoll BJ, Gordon T, Korones SB, Shankaram S, Tyson JE, Bauer CR, et al. Late-onset sepsis in very low birth weight neonates: a report from the National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr 1996; 129: 63-71.

  19. Yalaz M, Cetin H, Akisu M, Aydemir S, Tunger A, Kültürsay N. Neonatal nosocomial sepsis in a level-III NICU: evaluation of the causative agents and antimicrobial susceptibilities. Turk J Pediatr 2006; 48: 13-8.

  20. Coto CGD, Ibáñez FA. Protocolo diagnóstico-terapéutico de la sepsis neonatal. Bol Pediatr 2006; 46(Supl. 1): 125-34.

  21. Stoll BJ, Hansen N, Fanaroff AA, et al. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics 2002; 110: 285-91

  22. Norma Oficial Mexicana de Emergencia PROY-NOMEM- 045-SSA2-2005. Para la vigilancia epidemiológica, prevención y control de las infecciones nosocomiales. DGE, SSA. 2006.

  23. Coria LLJ, Gómez BD, Saavedra BMA. Avances en el control de infecciones nosocomiales en el paciente pediátrico. 2a. ed. Ed. México: Medicina & Mercadotecnia. AstraZeneca; 2005, p. 13-34, 173-81.

  24. Goldstein B, Giroir B, Randolph A. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 2005; 6: 2-8.

  25. Sarkar S, Bhagat I, DeCristofaro JD, Wiswell TE, Spitzer AR. A study of the role of multiple site blood cultures in the evaluation of neonatal sepsis. J Perinatol 2006; 26: 18-22.

  26. Ávila-Figueroa C, Cashat-Cruz M, Aranda-Patrón E, León A, Justiniani N, Pérez-Ricárdez L, et al. Prevalencia de infecciones nosocomiales en niños: encuesta de 21 hospitales en México. Salud Pub Mex 1999; 41(Supl. 1): S18-S25.

  27. Mesquita M, Hernández M. Infecciones nosocomiales en el neonato: índice de incidencia y factores de riesgo. Rev Pediatr 2003; 30: 1-6.

  28. Ballesteros OJC, Tena RD, García EG, Vega GA, Ramírez OMR, Sosa MJ, et al. Sensibilidad y especificidad del frotis de “buffy coat” teñido con Gram en el diagnóstico de sepsis neonatal. Rev Mex Pediatr 2008; 75; 97-102.

  29. OMS/CDC/CSR/EPH. Prevención de infecciones nosocomiales: Guía Práctica. 2002.

  30. Young TE, Mangum B. Neofax 2008. 21a. Ed. Montvale, New Jersey: Thomson Reuters; 2008, p. 1-79




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