Castellanos PML, Nocito MJ, Marchesi C, Garuti RA, Carmona CLE, Capelli L, Lustia MM, Carabajal G, Mazzini MA

Language: Spanish
References: 21
Page: 147-153
PDF size: 170.47 Kb.

ABSTRACT

Perforating dermatosis (DP) comprises a group of diseases characterized by the extrusion of dermic debris through the epidermis. It includes reactive perforating collagenosis, perforating folliculitis, elastosis perforans serpiginosa and Kyrle´s disease. It presents as multiple pruritic papulo nodules centered by a keratotic plug. Antihistamines, phototherapy and intralesional steroids are among the therapeutic options described, with variable results.
Objectives. To describe 8 cases of perforating dermatosis diagnosed in our department.
Materials and Methods. We conducted a retrospective, observational and descriptive study evaluating clinical and histological features and association with systemic disease, of the patients with a biopsy confirmed, perforating dermatosis between September 2006 and July 2010.
Results. Eight patients with perforating dermatosis were diagnosed. Of them, 5 (62,5%) were male and 3 female (37,5%). Mean age of presentation was 57,12 years (37-71 years); 6 (75%) corresponded to Kyrle´s disease and 2 (25%) to perforating folliculitis; 6 (75%) were associated with chronic renal insufficiency, 6 (75%) with diabetes mellitus, 1 (12,5%) with acute renal insufficiency and 6 (75%) with cardiovascular disease.
Conclusions. Although most of our patients had a history of chronic renal insufficiency or diabetes, as described in the literature, in one of them no associated disease was found. Furthermore, 75% of the patients presented with cardiovascular disease. Unlike previous reports, we found a greater incidence in men (62,5%) over women.

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