2009, Number 3
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ABSTRACTlntroduction. Corneal transplant is the most common allograft; its success rate depends on the preexisting corneal disease. The incidence of graft rejection in patients who underwent penetrating keratoplasty, according to the prognosis related group, in order to estimate the effect of interventions aimed at improving surgical results. Materiasl and methods. An observational, retrospective, longitudinal, analytic and open study was conducted in a general Hospital from Mexico City January 2003 and November 2006; we included eyes that hada penetrating keratoplasty with any preoperative diagnosis, with one year follow up, any gender or age, and assigned them to one of the four prognosis groups. The rejection incidence was identified, as well as the rate of rejection without involution at the end of follow up for each group; the analysis was done with rates and 95% confidence intervals. Results. 102 eyes of patients aged 4 90 years (mean 43.4 S. D. ± 2 1.50) 38 of group 1, 49 of group 2, 9 of group 3 and 6 of group 4. 23 eyes had a preoperative diagnosis of graft rejection (22.5%), 51 eyes hada rejection (50%), which did not disappear after one year in 28 eyes (27.5%). The incidence was 55.2% for group 1, 44.8% for 2, 44.4% for 3 and 66.7% for 4. A preoperative history of rejection did not change the incidence. Discussion. The rejection rate was high in the groups considered to have with better prognosis. Although most of the rejections reverted, the conditions that lead to this highly unexpected incidence should be identified.
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