Lima GV, Ramírez SC

Language: Spanish
References: 0
Page: 13-17
PDF size: 517.70 Kb.

ABSTRACT

Background. Treatment of clinically significant macular edema (CSME) relies on fluorescein angiography, to identify whether vascular leaking is focal or diffuse. Optical coherence tomography (OCT) measures retinal thickness quantitatively; a study was conducted to identify if the amount of thickening in the angiographic types of CSME al lowed their identification using OCT. Methods. Observational, comparative, cross sectional, retrospective and open label study. Diabetic patients aged 40 70 years with CSME, and an OCT fast macular map, obtained before treatment, were included. Patients with other macular disease or vitreous traction were excluded. The angiographie type was identified and 18 eyes were assigned to one of two groups: 1 (diffuse leakage) and 2 (focal leakage). Mean retinal thickness and macular volume were compared between groups using Mann Whitney's U; a ≥ 40% difference was considered clinically significant. Results. Mean retinal thickness in group 1 was statistically greater than that of group 2 in most retinal fields, in center point thickness (CPT, 320.7 ± 161.9 μm vs. 227.8 ± 116 μm, p = 0.03) and in macular volume (9.71 + 1. 95 mm3 vs. 8.13 + 1 .1 mm3, p = 0.003). Only CPT hada greater than 40% difference. Discussion. Differences of CPT and macular volume between angiographic types could allow their identification using OCT. OCT should eventual ly be evaluated to determine whether it can replace fluorescein angiography in plann ing the treatment of CSME with focal leakage.