Manrique MA, Juárez VEI, Chávez GMÁ, Pérez VE, Pérez CT, Álvarez CR, García MAR, Díaz GDC, Bellacetín FÓ, Téllez OA, Santamaría AJR, Cortés GME

Language: Spanish
References: 10
Page: 101-105
PDF size: 289.21 Kb.

ABSTRACT

Introduction. Chronic diarrhea is present in 4-5% of Western populations. The most common causes of microscopic colitis (CM) are infections, secondary to drugs and idiopathic disease and it becomes a frequent etiology of chronic diarrhea in elderly people. It characterized for aqueous chronic diarrhea with macroscopically normal colonoscopy and histopathologic alterations. It divides in both collagenous and lymphocytic colitis. It can be diagnostic in 10-20% of cases. The collagenous type affects more frequent to females. The lymphocytic has a relationship male:female 2-3:1. It has an unknown and multifactorial etiology, in which we found immunologic, genetics, infections, drugs, endoluminal factors, billiary acids, nitrous oxide and dysfunctional collagen synthesis. There are different types of treatments, being the first line of treatment budesonide. Objective. To determine the incidence of CM in patients with chronic diarrhea. Material and methods. We included all patients with diagnosis of chronic diarrhea underwent to colonoscopy and biopsy from January 2008 to October 2009 in the endoscopy department of Hospital Juarez de Mexico. Results. We included 61 patients, 26 males (42.6%), 35 females (57.3%), with an average of 49.9 years. We obtained only 3 patients with CM, 1 CL (1.6%) and 2 CG (3.2%). Conclusions. CM should considered in all patients with chronic diarrhea and macroscopically normal colonoscopy, is necessary to develop long term studies and included more patients to determine a real incidence of this pathology.

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