2011, Number 1
Rev Hosp Jua Mex 2011; 78 (1)
García ÁJ, Vega M, Torres J, Vázquez SD
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ABSTRACTGastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. Historically, these lesions were classified as leiomyomas or leiomyosarcomas, but the actual cell of origin of GISTs is a pluripotential mesenchymal stem cell programmed to differentiate into the interstitial cell of Cajal. These advances have led to the classification of GISTs as an entity separate from smooth muscle tumors. The case of 50-year-male patient with the diagnosis of gastrointestinal stromal tumor of the colon with infiltration jejunum and ileum is presented. The clinical manifestations, epidemiology and immunohistochemical diagnostic features are discussed. Finally, differential diagnosis and therapeutics are exposed.