Vargas AAS, Barbosa CRE, Barrera RAA, Casian CG, Balcázar VR

Language: Spanish
References: 7
Page: 187-190
PDF size: 255.76 Kb.

ABSTRACT

Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory rheumatic disorder. An incidence of 0.16 per 100,000 people is reported. In 75% of patients, symptoms begin between 16 and 35 years of age. The disease shows a female predominance (65- 70%). AOSD is characterized by fever, arthralgias, rash, leukocytosis with neutrophilia. The clinical course can be monocyclic (34%), polycyclic (24%) and chronic (30-50%). Case report. We report the case of a 33 year old female with a clinical picture characterized by fever, erythematous rash, cervical lymphadenopathy, hepatosplenomegaly, arthralgias and asymmetric arthritis in hands, elbows and knees. She presented with microcytic hypochromic anemia, leukocytosis, thrombocytosis, hypoalbuminemia, elevated serum ferritin and negative autoantibodies. Infectious, hematological and neoplasic diseases were excluded. The patient developed a chronic variant with erosions and carpal ankylosis Conclusion. AOSD is a diagnosis of exclusión. The chronic variant can cause severe disability due to severe joint disease.

REFERENCES

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