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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2013, Number 07

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Ginecol Obstet Mex 2013; 81 (07)

Report of the seminal characteristics in patients with consecutive pregnancy to intrauterine insemination and his perinatal complications

Kably-Ambe A, Campos-Cañas JA, González GE, Carballo E, Roque A
Full text How to cite this article

Language: Spanish
References: 6
Page: 365-369
PDF size: 545.90 Kb.


Key words:

Semen characteristics, pregnancy after intrauterine insemination, perinatal complications.

ABSTRACT

Background: It is reported that pregnancies achieved through assisted reproductive techniques have increased risk of complications. There is doubt as to whether this increase is attributable to the underlying infertility or to the assisted reproduction techniques. Postcapacitation seminal parameters have been mentioned as determinants of success.
Objectives: To describe semen parameters of patients at the Mexican Fertility Center (CEPAM) who achieved pregnancy with intrauterine insemination and compare the causes of perinatal morbidity and mortality with those of the general population.
Patients and Methods: A descriptive, retrospective (2004- 2009), analytical and longitudinal study based on analysis of intrauterine insemination cycles that achieved pregnancy with prenatal care and childbirth. The variables studied were: pregnancy, obstetric complications and postcapacitation semen parameters. For the analysis the data was divided according to sperm morphology. The results were analyzed using SPSS-20. Continuous variables were reported as means, and their standard deviations and logistic regression as univariate to determine the statistical significance. The categorical variables were evaluated in frequencies and percentages.
Results: 133 cases were analyzed, 78% with normal morphology over 4%, mean semen parameters: 0.63 mL volume, density 82.72 million/mL, progressive motility 88.5% and normal morphology over 4% of 5.93%. The 16.6% of pregnancies were twins. 18.5% was abortion, 69% was cesarean section and 30% vaginal delivery. No differences were found in any of the variables when comparing normal sperm morphology groups lower and higher than 4%, except in patients with abortion. There was no increased incidence of perinatal complications than in the general population.
Conclusions: Perinatal complications incidence is similar to the general population, except in multiple pregnancy. There is more success in intrauterine insemination when the postcapacitation morphology is over 4%.


REFERENCES

  1. The ESHRE Capri Workshop Group, Intrauterine Insemination. Hum Reprod Update 2009;15:265-277.

  2. Badawy A, Elnashar A, Eltotongy M. Effect of sperm morphology and number on success of intrauterine insemination. Fertil Steril 2009;91:777-781.

  3. Merviel P, Heraud M, Grenler N, et al. Predictive factors for pregnancy after intrauterine insemination (IUI): An analysis of 1038 cycles and a review of the literature. Fertil Steril 2008;1-10.

  4. Barros Delgadillo JC, Rojas Ruiz JC, Molina Munguía AC, Villalobos Acosta S, Sánchez Solís V, Barroso Villa G, Gaviño Gaviño F. Factores pronóstico de embarazo en inseminación intrauterina. Ginecol Obstet Mex 2006;74:611-625.

  5. Van Voorhis B, Barnett M, Sparks A, et al. Effect of the total motile sperm count on the efficacy and costeffectiveness of intrauterine insemination and in vitro fertilization. Fertil Steril 2001;75:661-668.

  6. De Sutter P, Veldeman L, Kok P, et al., Comparison of outcome of pregnancy after intrauterine insemination (IUI) and IVF. Human Reprod 2005;20:1642-1646.




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Ginecol Obstet Mex. 2013;81