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2013, Number 4

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Rev Mex Pediatr 2013; 80 (4)

Newborn with venous thrombosis by deficiency of C-reactive protein

Torres MM, Hernández HRJ

Language: Spanish
References: 12
Page: 142-145
PDF size: 130.41 Kb.


ABSTRACT

Neonatal thrombophilia is rare condition, and presents as deep vein thrombosis, pulmonary embolism or sudden death. There are multiple causes and few neonatal reports. This condition was observed in a 30 gestational week newborn with 1460 g of weight, the surfactant obtained good response. At 14 days presents apneas and perfusion changes precipitate ventilatory assistance. The 2 central catheters had obstruction and install subclavian catheter, but neck edema appears. A Doppler ultrasound confirmed thrombosis of superior cava vein and pulmonary gammagraphy the embolismo. Fresh frozen plasma and enoxaparin was administered. Thromobophilic profile reported a normal fibrinogen, but C Protein = 14% and rise up to 39% even a 3 daily dosis of fresh plasma. A low S Protein and Antithrombin III levels, normalized alter treatment.


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