2013, Number 2
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ABSTRACTThe main consequence of persistent replication of the human immunodeficiency virus is the gradual reduction of CD4 positive T lymphocytes, what eventually leads to the loss of immunological competence. The CD4 positive T lymphocytes count by means of flow cytometry is considered an essential part in medical attention and a parameter to identify the disease as well as a useful guide to clinical treatment. Numerous factors, besides the infection by the human immunodeficiency virus, can influence in the CD4 positive T lymphocytes. The changes in this parameter, generated by these factors, do not indicate real modifications in the immunological status of the patient and should be interpreted with caution.
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