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2013, Number 4

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Rev Med MD 2013; 4.5 (4)

Lupus nephritis and pregnancy, obstetric perspective

Barba-Jiménez AM, De León-Peguero NG
Full text How to cite this article

Language: Spanish
References: 8
Page: 289-293
PDF size: 620.99 Kb.


Key words:

pregnancy, hypertension, Systemic lupus erythematosus, lupus nephritis, intrauterine growth restriction.

ABSTRACT

A 17 years of age female patient, first-timer diagnosed with Systemic lupus erythematosus and Lupus Nephritis class IV proliferating diffuse since she was 10 years old, treated with prednisone, chloroquine, azathioprine, medicines that were suspended a year ago without medical indication. Coursing 18 weeks of pregnancy, initiates general discomfort, generalized edema, hypertension and skin lesions reason why she attends to prenatal control consultation. She is appraised and diagnosed with chronic renal disease (CRD) stage V second to Lupus Nephritis and admitted for kidney substitution therapy.
The Systemic lupus erythematosus is an autoimmune disease that mainly affects women on fertile age. The active renal affectation as Lupus Nephritis o a outbreak of SLE at the time of conception or new beginning during pregnancy is accompanied by an increase on maternal, fetal and neonatal morbidity-mortality, so is fundamental that patients with this pathology are closely observed for the achievement of better results for the binomial.


REFERENCES

  1. Bramham K, Soh MC and Nelson-Piercy C (2012) Pregnancy and renal outcomes in lupus nephritis: an update and guide management, Lupus 2012. 21; 1271-1283.

  2. Tood J. Stanhope, Wendy M. White et al. Obstetric Nephrology: Lupus and Lupus Nephritis in Pregnancy. Clin J Am Soc Nephrol 2012 7:2089-2099,

  3. Ruiz Irastorza Guillermo, Ezpinosa Gerard, Frutos Miguel A. Jiménez Alonso Juan et al. Diagnóstico y tratamiento de la nefritis lúpica. Documento de consenso del Grupo de Enfermedades Autoinmunes Sistémicas (GEAS) de la Sociedad Española de Medicina Interna (SEMI) y de la Sociedad Española de Nefrología (S.E.N.), Nefrologia 2012; 32 suppl(1): 1-35

  4. Weening JJ, D'Agati VD, Schwartz MM, Seshan SV, Alpers CE, Appel GB, Balow JE, et al. The classification of glomerulonephritis in systemic lupus erithematous revisited. J Am Soc Nephrol 2004;15:241-250, .

  5. Saavedra Miguel A., Cruz-Reyes Claudia, Vera- Lastra Olga, Romer Griselda T., Cruz-Cruz Polita et al. Impact of previous lupus nephritis on maternal and fetal outcomes during pregnancy. Clin Rehumatol 2012;31: 813-819

  6. Shur Peter H, Bermas Bonnie L, et al. Pregnancy in women with systemic lupus erythematosus. UptoDate Wellesley MA, 2012.

  7. Paul Jungers and Dominique Chauveau, Perspectives in renal medicine Pregnancy in renal disease. Kidney International 1997;52:871-885.

  8. Furaz-Czerpak Karina R., Fernández-Juárez Gema, et al. Embarazo en mujeres en diálisis crónica: revisión. Revista de nefrología 2012;32(3):287-94




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Rev Med MD. 2013;4.5