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Revista Mexicana de Neurociencia

Academia Mexicana de Neurología, A.C.
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2008, Number 4

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Rev Mex Neuroci 2008; 9 (4)

Non-Hodgkin Lymphoma of right maxillary sinus with central nervous system metastasis. Case report

Gutiérrez LC, Plascencia ÁNI, Quiñones AS, Venegas TA, Núñez OL
Full text How to cite this article

Language: Spanish
References: 7
Page: 310-312
PDF size: 182.75 Kb.


Key words:

non-Hodgkin lymphoma, brain parenchyma metastasis.

ABSTRACT

We present a case of a 30 years-old man who four years before had a non-treated tumour in right maxillary sinus. Afterwards, he begins with subacute neurological features with headache; complex partial seizures secondarily generalized which led to status epilepticus and cognitive dysfunction. MRI showed multiple lesions in frontal lobes. The histological diagnosis of the biopsy of maxillary sinus mucosa concluded non-Hodgkin lymphoma, so the lesions demonstrated in cranial MRI were diagnosed as metastasis. Previous reports inform less than 5% of metastasis to central nervous system from non Hodgkin lymphoma infiltrating leptomeninges and sparing brain parenchyma. For the contrary, this case has a severe involvement of frontal lobes, reason to present the case.


REFERENCES

  1. Masson-Punyet R, et al. Metástasis cerebrales. Rev Neurol 2000; 31(12): 1242-7.

  2. Bierman P. Diagnosis and treatment of central nervous system involvement in Non Hodgkin’s Lymphoma. Hematol Oncol Clin N Am 2005; 19(3): 597-609.

  3. Bashir RM, Bierman PJ, et al. Central nervous system involvement in patients with diffuse aggressive non Hodgkin’s lymphoma. Am J Clin Oncol 1991; 14(6): 478-82.

  4. Bollen EL, Brouwer RE, Hamers S, et al. Central nervous Non Hodgkin’s Lymphoma. A single study of 532 patients. Arch Neurol 1997; 54(7): 854-9.

  5. Shikama N, Oguchi M, et al. Evaluation of central nervous system involvement in nasal lymphomas. Nippon Acta Radiological 2001; 61(87): 342-6.

  6. Zhang, Jingfeng, et al. Extranodal imaging manifestations of Non Hodgkin lymphoma. Journal of Huazhong University of Science and Technology. Medical Science 2003; 23(3): 324-7.

  7. Ersboll J, Schutz HB, Thomsen GL, et al. Meningeal involvement in No Hodgkin’s Lymphoma symptoms, incidence, risk factors and treatment. Scand J Hematol 1985; 35(5): 487-96.




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C?MO CITAR (Vancouver)

Rev Mex Neuroci. 2008;9