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Revista de Endocrinología y Nutrición

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2012, Number 3

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Rev Endocrinol Nutr 2012; 20 (3)

Myxedema coma: A case report

Mena-Vela B, Zenteno-Ocampo E, Domínguez-Morales M
Full text How to cite this article

Language: Spanish
References: 6
Page: 113-115
PDF size: 315.83 Kb.


Key words:

Hypothiroidism, myxedema coma, SOFA (Score for Organ Failure).

ABSTRACT

Myxedema coma is the most exteme complication of hypothyroidism. Mortality ranges between 50 and 70%. Mexico has no epidemiological data about the prevalence of this condition. Pathogenesis of myxedema is not clear; the most common risk factors are infection, treatment omission or misused narcotics. Treatment is based on supplementation of levothyroxine. Hormonal pool recovers after the administration of 500 to 800 µg of levothyroxine and patients could recover in hours. We present the case of a 49 year old woman who was admitted to our hospital for extreme hypothyroidism and hours after she developed narcosis and coma.


REFERENCES

  1. Dutta P, Bhansali A, Masoodi S. Predictors of outcome in myxedema coma: a study from a tertiary care center. Crit Care. 2008; 12: R1.

  2. Vivek M, Ahmad R, Ghosh S. Myxedema coma: a new look into an old crisis. J Thyroid Res. 2011; 2011: 493462.

  3. Larsen KP. Melmed. Mixedema coma. En: Williams. Texto de endocrinología. 12va Edición. Saunders. Copyright 2011.

  4. Rebollo-Gómez H. Coma mixedematoso. Informe de caso. Rev Med Inst Mex Seguro Soc. 2010; 48: 215-217.

  5. Rodriguez I, Fluiters E, Pérez-Méndez LF, Luna R. Factor associated with mortality of patients with mixedema coma: prospective study in 11 cases treated in a single institution. J Endocrinol. 2004; 189: 347-350.

  6. Wartofsky L. Myxedema coma. Endocrinol Metab Clin N Am. 2006, 35: 687-698.




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Rev Endocrinol Nutr. 2012;20