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Revista Mexicana de Neurociencia

Academia Mexicana de Neurología, A.C.
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2009, Number 5

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Rev Mex Neuroci 2009; 10 (5)

Key data for clinical diagnosis of Parkinson’s disease

Bertado RN, Plascencia ÁN, Quiñones AS, Núñez OL
Full text How to cite this article

Language: Spanish
References: 7
Page: 340-343
PDF size: 71.21 Kb.


Key words:

Parkinson’s disease, rest tremor, bradykinesia, rigidity, asymmetric onset.

ABSTRACT

Introduction: Parkinson’s disease is the second cause of degenerative disorders in adult population. Since the diagnosis is purely clinic, it is very important to determine which are the key symptoms to confirm the disease. Objetive: To determine which were the criteria used to confirm the diagnosis in patients with Parkinson’s disease suspicion, sent to the CMN 20 de Noviembre. Material and methods: We reviewed 97 clinical records of patients with diagnosis of Parkinson´s disease, and registered the signs and symptoms found in the reference SM1-17 format, the first neurological examination using UPDRS, Schwab & England Scale, Hoenh & Yahr Scale, levodopa response and the absence of basal ganglia lesions by Magnetic Resonance Image (MRI). Results: We found rest tremor in all patients (100%), followed by bradykinesia (84.5%), rigidity (70.1%), and loss of postural reflexes (9.7%). It is mandatory to realice studies like MRI in order to discard basal ganglia lesions. We found cortical and subcortical atrophy related to the chronicity of the disease. Conclusion: Rest tremor is the most frequent symptom in our population plus bradykinesia, rigidity and asymmetric onset, which are the cardinal signs for the clinical diagnosis.


REFERENCES

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  2. Paulson HL, Matthew B. Clinical manifestation of Parkinson’s disease. In: Watts R, Koller W (eds.). Movement disorders: Neurologic Principles and Practice. The Mc Graw-Hill Companies, Inc.; 2004, p. 233-46.

  3. Jankovic J. Parkinsonism: Clinical features & differential diagnosis. In: Fahn S, Jankovic J, Hallett M, Jenner P (eds.). A comprehensive review of movement disorder for the clinical practitioner. The Movement Disorder Society; 2004, p. 353-405.

  4. Jackovic J. Progression of Parkinson’s disease. Are we making progress in charting the course? Arch Neurol 2005; 62: 351-2.

  5. Berendse HW, Booij J, Francot CM, Bergmans PL, Hijman R, Stoof JC, et al. Subclinical dopaminergic dysfunction in asymptomatic Parkinson’s disease patients relatives with a decrease sense of smell. Ann Neurol 2001; 50: 34-41.

  6. Powe W. Natural history and prognosis of Parkinson’s disease. Pathophysiology 1998; S(Suppl. 1): 232-8.

  7. Powe W. The natural history of Parkinson’s disease. J Neurol 2006; 253 (Suppl. 7): VII/2-VII/6.




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Rev Mex Neuroci. 2009;10