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Órgano Oficial de la Asociación Dental Mexicana

2004, Number 2

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Rev ADM 2004; 61 (2)

Immunological mechanisms involved in radicular cysts development: A review of the literature

Álvarez RP, ernandes Batista de Amorim R, Gordón-Núñez MA, Batista SL, Rejane Andrade CR

Language: Spanish
References: 35
Page: 54-58
PDF size: 67.24 Kb.


ABSTRACT

The periapical cyst is an inflammatory lesion of the jaws, it’s developed in the periapical area of teeth with pulp necrosis and infection, it is considered as a direct sequel of an apical granuloma. The cyst transformation occurs by stimulation of the epithelial rests of Malassez that are present in the periodontal ligament, as a response to an inflammatory stimuli. The advancement to the exterior of the pulp canals to the periapical area by bacteria and toxins leads to an immune response. The immune mechanisms are unleashed and relate directly with the pathogenesis of periapical cysts and the cell immune response, it is mediated primarily by T lymphocytes, as a humoral immune response, characterized by antibody production that are part of the process. This article is a literature review that focuses on the main immunologic events involved in the periapical cyst pathogenesis with the purpose of a better understanding of the biologic behavior of the lesion.


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