Chiquete E, Guareña-Serrano CO, Bañuelos-Becerra LJ, Leal-Mora D, Flores-Castro M, Ochoa-Guzmán A, Ruiz-Sandoval JL

Language: Spanish
References: 23
Page: 139-145
PDF size: 176.19 Kb.

ABSTRACT

Introduction: Despite the growth of the elderly population in Mexico, little information exists on the risk factors and prognosis of patients older than 80 years suffering acute ischemic stroke (AIS). Objective: To identify differences in the frequency of risk factors for AIS and outcome in patients aged ≥ 80 years and their younger counterparts in a reference hospital from Mexico. Methods: A cross-sectional analysis was performed on 238 adult patients with AIS: 56 (23.5%) aged ≥ 80 years and 182 (76.4%) patients aged ‹ 80 years, as comparators. Data were collected from the clinical records and risk factors and short-term outcome were analyzed. Results: There were no differences in gender proportion between both groups. Diabetes (55%) and hypertension (53%) were the main risk factors, but in patients aged ≥ 80 years diabetes had a significantly lower frequency than that of their younger counterparts (32 vs. 62%, respectively; p ‹ 0.001). In contrast, the frequency of atrial fibrillation was significantly higher in octogenarians than in comparators (37 vs. 12%, respectively; p ‹ 0.001). In a Cox proportional hazards model adjusted for relevant covariables, age ≥ 80 years (RR: 3.67, 95% CI: 1.82- 7.37) and the occurrence of septic shock (RR: 6.73, 95% CI: 3.19-14.20) were the factors associated with inhospital mortality. Conclusion: Octogenarians hospitalized with AIS have a lower frequency of some vascular risk factors, but a higher risk for in-hospital mortality, when compare with younger individuals.

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