Beltrán DY, Morris QHJ, Reynaldo CE, Quevedo MY, Bermúdez SRC

Language: Spanish
References: 16
Page: 121-129
PDF size: 211.08 Kb.

ABSTRACT

Background: Edible mushrooms have been used since the immemorial because of their nutritional and pharmacological properties.
Objective: Immunomodulating effects of three preparations of fruit bodies have been investigated with the aim of developing new formulations of therapeutic value from Pleurotus in Cuba.
Methods: In this research, the content of total phenols was determined in five extracts of fruit bodies of Pleurotus sp. mushrooms, obtained with solvents of different polarity: n-hexan, ethyl acetate, acetone, ethanol and water. The content of polyphenols was determined using the Folin-Ciocalteu reagent. The data related to the content of total solids in the extracts were processed by a simple analysis of variance (ANOVA).
Results: The concentration of total solids was higher in the aqueous and ethanolic extracts, with three and five times higher values than the ones obtained with less polar solvents (p‹0.05). Phenolic compounds were detected in the five extracts; however, the highest levels were found in those obtained with the most polar solvents (water and ethanol) with values of 138.4 and 86.37 mg/100 g, dry base, respectively (p‹0.05). A positive correlation between the phenol contents and the solvent dielectric constant was observed (r= 0.92).
Conclusions: The results suggest the evaluation of the antioxidant activity of the polar fractions of fruit bodies of Pleurotus both in "in vitro" and "in vivo" models.

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