Mendoza-Sánchez F, Oberholzer J, Herrera-Rodríguez R, Muñoz-Magallanes MT, Rodríguez-Reynoso S, Pelayo-Orozco LÁ, Sandoval-Alvarado J, Gómez-Navarro B

Language: Spanish
References: 17
Page: 73-76
PDF size: 188.33 Kb.

ABSTRACT

Introduction: Pancreas-kidney transplantation is a recommended treatment for diabetic insulin with end-stage nephropathy chronic disease. According to the International Pancreas Transplant Registry more than 35,000 transplants of pancreas have been realized, more than 24,000 in USA and almost 12,000 out of USA. In Mexico there are no publications of casuistry. We present the first case of a successful transplantation pancreas-kidney in Mexico. Case Presentation: A 33-year-old masculine patient with diagnosis of diabetes mellitus type I and renal chronic insufficiency of five years of evolution. The preoperative levels of creatinine were of up to 20 mg/dL and glycosylated hemoglobin of 9.5%. The donor was a masculine of 17 years old with cerebral death secondarily to skull-encephalic traumatism. The times of warm isquemia were 42 and 46 minutes for pancreas and kidney respectively. The times of cold isquemia of 10:30 and 11:15 hours, respectively. The scheme immunosupressive was based in basiliximab, metilprednisolone, tacrolimus and mophetilmicophenilato. The levels of postoperative creatinine normalized, the renal function was 72.59 mL/min in the first month and increased up to 82.29 at two years postransplant. The hemoglobin glucosilada decreased to 5.4%, and persist with low levels since then. At present, 9 years after, he is asymptomatic, without support with exogenous insulin. Conclusion: Pancreas-kidney transplantation in our country is a procedure that can be done with very good results and good survival.

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