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Archivos de Medicina de Urgencia de México

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ISSN 2007-1752 (Print)
Archivos de Medicina de Urgencia de México
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2013, Number 2

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Arch Med Urg Mex 2013; 5 (2)

Methemoglobinemia induced by dapsone intake for suicide attempt purposes. A propos of a case

Nares TMÁ, Arredondo AJM, Ferrari GS, Sánchez VMC
Full text How to cite this article

Language: Spanish
References: 9
Page: 85-88
PDF size: 174.60 Kb.


Key words:

Methemoglobinemia, dapsone, suicide.

ABSTRACT

Dapsone is a commonly prescribed leprostatic agent for the treatment of patients with leprosy, malaria, and a variety of skin diseases. Methemoglobinemia, a potentially life threatening when the oxygen carrying capacity of blood in the body tissues is reduced, is a known adverse effect of dapsone use. We report a case of dapsone induced Methemoglobinemia observed in the Emergency Service of Hospital General, Centro Médico Nacional la Raza, in a patient with vitiligo treated with dapsone and taking this for purposes of attempting suicide. The pathophysiological mechanisms, diagnosis, and treatment of dapsone-induced methemoglobinemia will be discussed.


REFERENCES

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  3. Avner JR, Henretig FM, Mc Aneney CM. Acquired methemoglobinemia. Am J Dis Child. 1990; 144: 1229-1230.

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  5. Wilson CM, Bird SG, Bocash W, Yang LL, Meritt RS. Methemoglobinemia following metoclopramida therapy in an infant. J Pediatr Gastroenterol Nutr. 1987; 6: 640-642.

  6. Wilburn-GD, Lloyd LM. When patients become cyanotic: acquired metahemoglobinemia. J Am Dent Assoc. 1999; 130: 826-831.

  7. Lynch A, Tobías JD. Acute valproate ingestión induces symptomatic methemoglobinemia. Pediatr Emerg Care. 1998; 14: 205-207.

  8. Erickson T, Zell-Kanter. Metahemoblobinemia. En: Strange GR. Medicina de urgencias pediátricas. USA: Mc Graw Hill-Interamericana; 1998: 596-597.

  9. Clifton J, Leikin JB. Methylen blue. Am J Ther. 2003; 10: 289-291.




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Arch Med Urg Mex. 2013;5