González GMB, Linares VC, Rivera MS, Martínez MG, Murrieta PJF, Sánchez GME, Morales JR

Language: Spanish
References: 20
Page: 239-245
PDF size: 259.26 Kb.

ABSTRACT

Objectives: To determine the frequency of salivary gland tumors and their likely association with certain clinical features. Study design: A retrospective, cross-sectional, descriptive study was carried out at the oral histopathology laboratory of the Autonomous Metropolitan University in Xochimilco, Mexico City, from January 1979 to June 2012. The biopsies received were reviewed. The histopathological diagnoses of salivary gland tumors were assessed by three oral pathologists using the histological criteria proposed by the WHO. Clinical data were obtained from the study’s application form. A descriptive analysis was performed; prevalence rates were estimated and χ² and Fisher’s exact tests were used to allow comparison between groups. Results: Of the 9,725 biopsies received during the period of the study, 1% (96) of the cases involved salivary gland tumors. The age range of the patients was 11-90 years. Of the tumors found, 68.8% were benign and 31.2% malignant. Benign neoplasms were more prevalent in the 21-30 age group, whilst malign neoplasms were more prevalent in the 61-70 age group. The most common site was the palate, with 32 cases (33.3%) and the most prevalent color was yellowy-white with 30 (31.2%). There was a statistically significant relationship between being female and the presence of benign tumors (χ² = 8.9946; р = 0.003). The most common benign salivary gland tumor was the pleomorphic adenoma (93.9%) and the most common malignant tumor was the mucoepidermoid carcinoma (46.7%). Conclusions: Benign salivary gland tumors were more common and particularly affected women in their third decade of life. We recommend that a multicenter research study be undertaken in order to expand our knowledge of the epidemiological profile of salivary gland tumors.

REFERENCES

1. Ansari MH. Salivary gland tumors in an Iranian population: a retrospective study of 130 cases. J Oral Maxillofac Surg. 2007; 65: 2187-2194.

2. Ellis GL, Auclair PL. Tumors of the salivary glands. Atlas of tumor pathology, Third Series. Fascicle 17. Armed Forces Institute of Pathology; Washington D.C. 1996.

3. Evenson JW, Auclair P, Gnepp DR, El-Naggar AK. Tumors of the salivary glands: introduction. In: Barnes L, Evenson JW, Reichart P, Sidransky D. Pathology and genetic. Head and neck tumours. World Health Organization Classification of Tumors. Lyon. Ed. IARC Press; 2005: pp. 212-280.

4. Barnes L, Evenson JW, Reichart P, Sidransky D. Pathology and genetic. Head and neck tumours. World Health Organization Classification of Tumours. Lyon. Ed. IARC Press; 2005: p. 210.

5. Dhanuthai K, Boonadulyarat M, Jaengjongdee T, Jiruedee. A clinicophatologic study of 311 intra-oral salivary gland tumors in Thais. J Oral Pathol Med. 2009; 38: 495-500.

6. Bello OI, Salo T, Dayan D, Tervahauta E, Almangoush A, Schnaiderman-Shapiro A et al. Epithelial salivary gland tumors in two distant geographical locations, Finland (Helsinki and Oulu) and Israel (Tel Aviv): a 10-year retrospective, comparative study of 2,218 cases. Head and Neck Pathol. 2012; 6: 224-231.

7. Long-Jiang L, Yi L, Yu-Ming W, Hua L, Hong-Wei Z. Clinical analysis of salivary gland tumor cases in West China in past 50 years. Oral Oncol. 2008; 44: 187-192.

8. Mudiyanselage TW, Rukmal JP, Mudiyanselage TPBT, Saku T. Epithelial salivary tumors in Sri Lanka: a retrospective study of 713 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009; 108: 90-98.

9. Ledesma MC, Garcés OM. Tumores de glándulas salivales en México: estudio retrospectivo. Medicina Oral. 2002; 7: 324-330.

10. Buchner A, Merrell PW, Carpenter WM. Relative frequency of intra-oral minor salivary gland tumors: a study of 380 cases from Northern California and comparison to reports from other parts of the world. J Oral Pathol Med. 2007; 36: 207-214.

11. Oliveira AF, Barroso DEC, Teixeira TC, Abreu MA, Carvalho de AE, Alencar RdeC, Franco VE. Salivary gland tumor: a review of 599 cases in a Brazilian population. Head and Neck Pathol. 2009; 3: 271-275.

12. Subhashraj K. Salivary gland tumors: a single institution experience in India. Br J of Oral and Maxillofac Surg. 2008; 46: 635-638.

13. Pires RF, Pringle AG, Paes de AO, Chen SY. Intra-oral minor salivary gland tumors: A clinicopathological study of 546 cases. Oral Oncol. 2007; 43: 463-470.

14. Tian Z, Li L, Wang L, Hu Y, Li J. Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6,982 cases in an Eastern Chinese population. Int J Oral Maxillofac urg. 2010; 39: 235-242.

15. Mejía-Velázquez CP, Durán-Padilla MA, Gómez-Apo E, Quezada-Rivera D, Gaytán-Cepeda LA. Tumours of the salivary gland in Mexicans. A retrospective study of 360 cases. Ned Oral Pathol Oral Cir Bucal. 2012; 17: e183-e189.

16. Lukšić I, Virag M, Manojlović S, Macan D. Salivary gland tumours: 25 year of experience a single institution in Croatia. J Craniomaxillofac Surg. 2012; 40: e75-e81.

17. Fonseca PF, de Vasconcelos CM, Paes de AO, Ayroza R CAL, Hirata TAM, Galvão BA. Clinicopathologic analysis of 493 cases of salivary gland tumors in a Southern Brazilian population. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012; 114: 230-239.

18. Ledesma MC; Garcés OM. Malignant salivary gland tumors. Revista del Instituto Nacional de Cancerología. 2000; 46: 167-170.

19. Kasangaki A, Kumulegeya A. Neoplasms of salivary: a descriptive retrospective study of 142 cases-Mulago Hospital Uganda. The Journal of Contemporary Dental Practice. Consultado 12 diciembre 2012, en: www.Thejcdp.com. 2004; 5: 16-27.

20. Otoh EC, Johnson NW, Alasoji H, Danfillo IS, Adeleke OA. Salivary gland neoplasms in Maiduguri, North-Eastern Nigeria. Oral Dis. 2005; 11: 386-391.