Tiribelli C

Language: English
References: 0
Page: 4-5
PDF size: 27.42 Kb.

Text Extraction

Combination of Peg-interferon… by Amarapurkar DN et al.

This study reports on the effect of treatment with Peginterferon α-2b (PegIFN) and lamivudine in Indian patients with chronic liver disease related to HBV infection. In spite of the very limited number of patients enrolled, they were divided into 4 different groups according to the HBV serology (HBeAg positivity or negativity) and past history of IFN treatment (naïve or already treated with IFN without viral clearance). Treatment lasted for 6 months and response was defined as sustained clearance of the virus (SVR) 6 months after stop of the IFN administration. Intriguing was the observation that in all groups, SVR was quite remarkable varying between 50 to 60% with the only exception of HBsAg positive, previously treated subjects where percentage was somehow lower that 30%.