2013, Number 5
Rev Mex Neuroci 2013; 14 (5)
Evaluation of mesial temporal structures supporting memory functions with Wada test using propofol in patient’s candidates to epilepsy surgery in Cuba: a case report
Andrade MR, Goicoechea AA, Llibre GJC, Jordán GJA, López JM, Amílcar SDM, Pino FI, Fuentes SZ, Estrada VG
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ABSTRACTIntroduction: The reports on the execution of Wada test with propofol instead amobarbital in patients with left temporal lobe Epilepsy, let us to incorporate this procedure as part of prersurgical evaluation in patients with refractory epilepsy.
Objective: Describe the implementation of Wada test with propofol in our country to evaluate both the lateralization of language functions and the memory reserve in patients with left temporal lobe epilepsy in Cuba.
Case Report: We report two patients with left temporal lobe epilepsy evaluated in the video-monitoring unit at epilepsy section in the National Neurology Institute of Cuba. One patient has a bilateral temporal lobe dysfunction judged by the features of severe visual and verbal memory impairment. The second patient has severe impairment in verbal memory and his MRI showed a bilateral hipocampal dismorfia. The Wada test demonstrated a good verbal memory reserve in both patients. A standard anterior left temporal lobectomy was carried out without complications in both patients. Eight months after surgery the patients were seizure free and no decline in verbal memory was documented.
Conclusions: The Wada test permits to evaluate the functional reserve of memory. Propofol appears to be a useful drug for completion of Wada test, giving similar results to those obtained with the use of sodium amobarbital.