2013, Number 3
Rev Hematol Mex 2013; 14 (3)
López A, González-Llano Ó, Ramírez AC, Corolla M, Gómez-Almaguer D, Alvarado Y
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ABSTRACTNon-Hodgkin lymphoma (NHL) and Hodgkin disease are the third cause of cancer in childhood. The testis involvement as an initial manifestation is rare at this age, so it is not usually considered as a differential diagnosis in children with testicular tumor. We present a five years old child with increase in size in left testicle, with no other symptoms. Orchiectomy was performed. The pathology report was positive for B-cell lymphoblastic lymphoma with the following markers CD10, TdT, CD34, PAX5. In the extension studies, infiltration in central nervous system and bone marrow was negative. We classified the disease as stage II of the staging system of St. Jude’s Hospital. We started treatment with the COG 5971 protocol and obtained, until now, very good results. Good prognosis is related to a prompt diagnosis and therapeutic intervention.