2013, Number 4
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ABSTRACTQuantification of leukocyte populations in peripheral blood can be performed using flow cytometry. The leukocyte populations are often contrasted between neonate and adult peripheral blood. This preliminary report shows the analysis of three samples of umbilical cord blood of healthy subjects and three peripheral blood samples of newborns diagnosed with late sepsis. Our results show that CD69, CD71 and CD45RO could be useful to differentiate states of sepsis in neonates. We propose a subsequent study to generate a multiparametric flow cytometry analysis that will allow a comprehensive analysis of neonatal sepsis.
Morgado JM, Pratas R, Laranjeira P, Henriques A, Crespo I, Regateiro F et al. The phenotypical and functional characteristics of cord blood monocytes and CD14 -/low/CD16+ dendritic cells can be relevant to the development of cellular immune responses after transplantation. Transpl Immunol. 2008; 19: 55-63.