Rocha MJ, Bustos CE, Solís SK, Bustillo HCL, Pineda BLG

Language: Spanish
References: 10
Page: 232-237
PDF size: 229.40 Kb.

ABSTRACT

Introduction: There is limited information on schemes of erythrocyte concentrate transfusion in children with severe anemia (hemoglobin ≤ 5 g/dL) when started gradually and without cardiac decompensation. 1 mL/kg/h usual speed is associated with a prolonged time of transfusion. The main complication that can occur during the procedure is congestive heart failure. Methods: Two erythrocyte concentrate transfusion regimens (1 mL/kg/h and 3 mL/kg/h) was compared in a group of patients aged 1 month to 18 years with severe isovolemic anemia in the Emergency Department of the Hospital Infantil de México «Federico Gómez» from December 2010 to June 2011. Considering congestive heart failure when the patient had three or more of the following parameters: a) increased heart rate or breathing, b) respiratory distress, c) crackles, d) jugular venous distension and, e) hepatomegaly. Results: At the end of the transfusion, out of 36 patients studied, mean age 89 months (1 mL/kg/h group) and 86 months (3 mL/kg/h group), p = 0.156. Initial Hb (1 mL/kg/h group) was 4.30 g/dL and 4.03 g/dL for the 3 mL/kg/h group (p = 0.327). The most prevalent clinical condition was infiltrative syndrome. Not patient showed congestive heart failure during transfusion. Conclusions: The proposed treatment (3 mL/kg/h) is as safe and more effective than the usual one (1 mL/kg/h).

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