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2013, Number 2

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Rev Mex Med Fis Rehab 2013; 25 (2)

Six-minute walk test to evaluate effect of botulinum toxin A (Dysport™) in children with spastic gait

Aboytes-Meléndez CA, Serna-Valdés RE, Díaz-Gómez A, Huazano-García F

Language: Spanish
References: 26
Page: 49-53
PDF size: 264.02 Kb.


ABSTRACT

Chemodenervation with botulinum toxin type A is commonly used treatment for spasticity. Six minute walk test has been used to evaluate the outcome of spasticity treatment in children and is the best available test to assess walk endurance. The aim of this study was to demonstrate that the injection of botulinum toxin A in the gastrocnemius muscles in children improves walking. Material and methods: This is a non-randomized clinical trial undertaken from March through August 2011 in children that had not received botulinum toxin within six months before the study. Six minute walk test was applied as stated by the American Thoracic Society, before injection of toxin, and one week, one month and three months after that. Statistical analysis was done with Wilcoxon’s ranked pair test. Results: Seven children were included. Mean distance (median) at the basal measurement was 198.4 ±105.0 m (179.1), 216.2 ± 115.3 m (171.7) one week after, and 242.1 ± 133.1 m (168.2) and 228.2 ± 112.2 m (175.7) at one and three months after injection of BoNT A respectively, and we found statistical difference between basal and final measurements. Conclusion: We can conclude that botulinum toxin A minimally improves walking by assessing six minute walk test.


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