Trujillo GP, Dubey LA, Ramírez OA, Arreguín V, Macías AE, Muñoz JM, Macías JH, Mosqueda JL

Language: English
References: 18
Page: 399-402
PDF size: 132.09 Kb.

ABSTRACT

Background. The detection of asymptomatic bacteriuria in preadolescent girls may be important due to its effects on subsequent pregnancies. Objective. To describe the prevalence of asymptomatic bacteriuria in preadolescent girls and the value of the nitrite test for screening. Material and methods. Cross-sectional study in girls aged 9 to 13 years. Bacteriuria was defined as the growth of › 100,000 CFU/mL in 2 consecutive urine specimens. Results. Three hundred and twenty seven girls were included. Asymptomatic bacteriuria was found in 7 girls, so the prevalence was 2.1% (95% CI, 1 to 4.4%). Escherichia coli was the isolated agent in all the cases. Focused interrogatory found history of urinary symptoms in 6 girls. The utility values of the nitrite test were: sensitivity, 1; specificity, 0.9; positive likelihood ratio, 10; and negative predictive value, 1. Conclusions. The prevalence of asymptomatic bacteriuria in preadolescent girls in this Mexican study is similar to the one reported internationally; it is reasonable to consider its early detection to avoid its effects on future pregnancies. Nitrite test seems to be good for screening.

REFERENCES

1. Kass EH. Bacteriuria and the diagnosis of infections of the urinary tract. Arch Intern Med 1957; 100: 709-14.

2. Nicolle L, Bradley S, Colgan R, Rice J, Schaeffer A, Hooton T. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005; 40: 643-54.

3. Evans DA, Williams DN, Laughlin LW, et al. Bacteriuria in a population-based cohort of women. J Infect Dis 1978; 138: 768-73.

4. Kunin CM, McCormack RC. An epidemiologic study of bacteriuria and blood pressure among nuns and working women. N Engl J Med 1968; 278: 635-42.

5. Nicolle LE. Asymptomatic bacteriuria, important or not. N Engl J Med 2000; 343: 1037-9.

6. Zhanel G, Harding GKM, Nicolle LE. Asymptomatic bacteriuria in diabetics. Rev Infect Dis 1991; 13: 150-4.

7. Nicolle LE. Asymptomatic bacteriuria, when to screen and when to treat. Infect Dis Clin N Am 2003; 17: 367-94.

8. Alwall N. On controversial and open questions about the course and complications of non-obstructive urinary tract infection in adult women. Acta Med Scand 1978; 203: 369-77.

9. Tencer J. Asymptomatic bacteriuria-a long term study. Scand Jour Urol Nephrol 1988; 22: 31-4.

10. Mittendorf R, Williams MA, Kass EH. Prevention of preterm delivery and low birth weight associated with asymptomatic bacteriuria. Clin Infect Dis 1992; 14: 927-32.

11. Romero R, Oyarzun E, Mazor M, Sirtori M, Hobbins JC, Bracken M. Meta-analysis of the relationship between asymptomatic bacteriuria and preterm delivery/low birth weight. Obstet Gynecol 1989; 73: 576-82.

12. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement. CLSI 2012; document M100-S22.

13. McLachlan MS, Meller ST, Jones ER, et al. Urinary tract in school girls with covert bacteriuria. Arch Dis Child 1975; 50: 253-8.

14. Newcastle Asymptomatic Bacteriuria Research Group. Asymptomatic bacteriuria in schoolchildren in Newcastle upon Tyne. Arch Dis Child 1975; 50: 90-102.

15. Macejko AM, Schaeffer AJ. Asymptomatic bacteriuria and symptomatic urinary tract infections during pregnancy. Urol Clin N Am 2007; 34: 35-42.

16. Mittendorf R, Williams MA, Kass EH. Prevention of preterm delivery and low birth weight associated with asymptomatic bacteriuria. Clin Infect Dis 1992; 14: 927-32.

17. Romero R, Oyarzun E, Mazor M, Sirtori M, Hobbins JC, Bracken M. Meta-analysis of the relationship between asymptomatic bacteriuria and preterm delivery/low birth weight. Obstet Gynecol 1989; 73: 576-82.

18. Kuczmarski RJ, Ogden CL, Guo SS, et al. 2000 CDC growth charts for the United States: Methods and development. National Center for Health Statistics. Vital Health Stat 2002; 11(246).