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>Journals >Revista Médica MD >Year 2013, Issue 2

Betancourt-Sánchez F, Rodríguez-Chávez JL, Castańeda-Huerta ND, Aldana-Ledesma JM, Pinedo-Gómez J, Barbosa-Mederos B, Velarde-Ruiz VJA
Unspecified chronic ulcerative colitis and primary sclerosing cholangitis: Relation between both pathologies as a phenotype different to the inflammatory bowel disease. Case report
Rev Med MD 2013; 4.5 (2)

Language: Espańol
References: 5
Page: 107-110
PDF: 977.84 Kb.

[Full text - PDF]


The primary sclerosing cholangitis is a progressive disorder, cholestasic, characterized by chronic inflammation and formation of bile duct stenosis. The average age of the diagnosis ranges between the ages of 35 and 47, 62 to 70% of the patients are male. The symptoms include itching, fatigue, and in advanced cases ascendant cholangitis, cirrhosis and terminal liver failure. The bile ducts, gallbladder, liver and colon. The majority of the patients with primary sclerosing cholangitis also have an inflammatory bowel disease, and generally ulcerative colitis. This is the case of a male patient with chronic inflammatory diarrhea and biochemical cholestasic profile. On the colonoscopy there are data of ulcerative colitis and the cholangioresonance data, primary sclesosing cholangitis. The treatments starts with mesalazine and ursodeoxycholic acid having a favorable evolution.

Key words: primary sclerosing cholangitis, inflammatory bowel disease, ulcerative colitis.


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  2. Singh S, Talwalkar, JA. Primar y Sclerosing Cholangitis: Diagnosis, Prognosis, and Management. Clin Gastroenterol Hepatol 2013; 11:898-907.

  3. Trivedi P.J, Chapman R.W. PSC, AIH and overlap syndrome in inflammatory bowel disease: Clin Res Hepatol Gas 2012; 36, 420-436.

  4. Marelli L, Xirouchakis, E, Kalambokis, G, et al. Does the severity of primary sclerosing cholangitis influence the clinical course of associated ulcerative colitis? Gut 2011;60(9):1224—8.

  5. Karlsen T.H. Boberg, K.M. Update Primary Sclerosing Cholangitis: J Hepatol 2013; 59: 571-582.

>Journals >Revista Médica MD >Year 2013, Issue 2

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