Incidence and tendency of cervical-uterine lesions in Pinar del Rio 10-to-14-year-old women, 2003-2012

José Guillermo Sanabria Negrín; Salgueiro Medina Victor E; Abreu Mérida M B; Agustín Lemus Sarracino; Raydel Marrero Fernández

2014, Number 1

<< Back Next >>

Rev Ciencias Médicas 2014; 18 (1)

Incidence and tendency of cervical-uterine lesions in Pinar del Rio 10-to-14-year-old women, 2003-2012

Sanabria NJG, Salgueiro MVE, Abreu MMB, Lemus SA, Marrero FR

Full text

How to cite this article

Language: Spanish
References: 16
Page: 4-13
PDF size: 172.34 Kb.

ABSTRACT

Introduction: malignant and pre-malignant lesions have been localized in women less than 25 years, but the exact enormity of the problem in Pinar del Río is not known.
Objective: to evaluate the tendency and incidence of malignant and pre-malign cervical lesions in Pinar women less than 25 years old according to demographic characteristics, in the period 2003-2012.
Material and method: a retrospective, cross-sectional study was carried out, in order to know the annual incidence of malign and pre-malign cervical lesions in Pinar women younger than 25 years. The sample comprised the results of biopsies made of those women in that period.
Results: the annual incidence in 10,000 women from 10-24 years old was 8.8 for CIN1, 3.1 for CIN2, 1.6 for CIN3 + CIS (carcinoma in situ), 0.07 for de microinvasive, 0.03 for the invasive Ib, and 0.02 for the invasive stage II. Stages over neither epidermoidal nor endocervical adenocarcinomas were detected. The annual incidence in each lesion proved increasing particularly for NIC1 cases. Out of 1,198 biopsies made on this age group, only 10 invasive epidermoidal carcinomas were detected in ten years, 0.7 annually, with a proportion of 5.8 per 1,000 women between 10-24 years of age.
Conclusions: The tendency of malignant lesions detected in this group would not justify starting the cytological screening before the 25 years of age, since the cost would high and the benefit would be minimal.

REFERENCES

Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010 Dec 15; 127(12).
Insinga RP, Dasbach EJ, Elbasha EH. Epidemiologic natural history and clinical management of Human Papillomavirus (HPV) Disease: a critical and systematic review of the literature in the development of an HPV dynamic transmission model. BMC Infectious diseases. 2009; 9.
de la Torre Rendón FE. Lesión premaligna escamosa del cuello uterino, un enfoque actualizado. Patología. 2008; 46(4).
Crane M. CDC: HPV vaccine is lowering infection rates in teen girls. Medscape Mecial News.
Insinga RP, Dasbach EJ, Elbasha EH. Epidemiologic natural history and clinical management of Human Papillomavirus (HPV) Disease: a critical and systematic review of the literature in the development of an HPV dynamic transmission model. BMC Infectious diseases. 2009; 9.
Moscicki AB. Management of adolescents with abnormal cytology and histology for OBGYN Clinics of North America. Obstet Gynecol Clin North Anm. 2008; 35(4).
Winer RL, Lee SK, Hughes JP, Adam DE, Kiviat NB, Koutsky LA. Genital Human Papillomavirus Infection: Incidence and Risk Factors in a Cohort of Female University Students. Am J Epidemiol. 2003; 157 (3).
Case AS, Rocconi RP, Straughn JM Jr, Wang W, Roark K, Waltman EE, et al. Cervical intraepithelial neoplasia in adolescent women: incidence and treatment outcomes. Obstet Gynecol. 2006 Dec; 108(6).
Cabeza CE. Programa Nacional de Diagnóstico Precoz del Cáncer Cervicouterino. La Habana: Editorial de Ciencia Médicas; 2001. Actualizado en 2011 (en prensa)
Moscicki AB, Ma Y, Wibbelsman C, Powers A, Darragh TM, Nozzari S, et al. Risks for cervical intraepithelial neoplasia-3 among adolescent and young women with abnormal cytology. Obstet Gynecol. 2008 Dec; 112(6).
Rodríguez AC, Schiffman M, Herrero R, Wacholder S, Hildesheim A, Castle PE, et al. Rapid clearance of HPV and implications for clinical focus on persistent infections. JNCI. 2008; 100(7).
Daudinot Cos CE, Rodríguez Spínola A, Sáez Cantero Vde la C, De la Torre Jiménez AI. Caracterización de las lesiones intra-epiteliales cervicales de alto grado en adolescentes y mujeres jóvenes. Medisur. 2011; 9(5).
Zhao C, Kalposi-Novak P, Austin M. Follow-up findings in young females with high-grade squamous intraepithelial lesion Papanicolaou test results. Arch Pathol Lab Med. 2011; 135.
Moscicki AB, Cox JT. Practice improvement in cervical screening and management (PICSM): Symposium on Management of Cervical Abnormalitis in Adolescents and Yong Women. J Low Genit Tract Dis. 2010 Jan; 14(1).
Martínez Chang YM, Sarduy Nápoles M. Manejo de las adolescentes con neoplasia intraepitelial cervical. Rev Cubana Invest Bioméd. 2006; 25(1).
Hilton S, Smith E. I thought cancer was one of those random things. I didn´t know cancer could be caught… Adolescent girls´understanding and experiences of the HPV programme in the UK. Vaccine. 2011 June 10; 29(26).