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2005, Number 4

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Rev Inst Nal Enf Resp Mex 2005; 18 (4)

A positive sputum smear test is not always indicative of pulmonary TB. Another reason to order routine cultures

Laniado-Laborín R, Cabrales-Vargas N
Full text How to cite this article

Language: Spanish
References: 13
Page: 286-299
PDF size: 54.64 Kb.


Key words:

Ziehl-Neelsen stain, false positive, tuberculosis, nocardiosis.

ABSTRACT

The Ziehl–Neelsen (ZN) stain is rapid and economic technique for the identification of acid-fast organisms, primarily Mycobacterium tuberculosis. However, the presence of acid-fast bacilli can not be considered as proof of tuberculosis; there is a wide variety of acid-fast microorganisms including non-tuberculous mycobacteria and even Nocardia spp and this could be a cause of misidentification. To illustrate this point, we present a patient with pulmonary nocardiosis and another with non-tuberculous mycobacteriosis that were initially misdiagnosed and treated for tuberculosis.


REFERENCES

  1. American Thoracic Society. Diagnostic Standards and Classification of Tuberculosis in Adults and Children. Am J Respir Crit Care Med 2000;161(4 Pt 1):1376-1395.

  2. Modificación a la Norma Oficial Mexicana NOM-006-SSA2-1993, para la prevención y control de la tuberculosis en la atención primaria a la salud. Diario Oficial. México. 31 de octubre, 2000.

  3. Olson ES, Simpson AJ, Norton AJ, Das SS. Not everything acid fast is Mycobacterium tuberculosis. A case report. J Clin Pathol 1998;51:535-536.

  4. Katoch VM. Infections due to non-tuberculous mycobacteria (NTM). Indian J Med Res 2004;120:290-304.

  5. American Thoracic Society. Diagnosis and treatment of disease caused by nontuberculous mycobacteria. Am J Respir Crit Care Med 1997;156(2 Pt 2):1-25.

  6. Menendez R, Cordero PJ, Santos M, Gobernado M, Marco V. Pulmonary infection with Nocardia species: a report of 10 cases and review. Eur Respir J 1997;10:1542-1546.

  7. World Health Organization. Treatment of tuberculosis guidelines for national programmes. 2nd ed. WHO/TB/97.220. Geneva, Switzerland: World Health Organization: 1997.

  8. International Union against Tuberculosis and Lung Disease. Management of tuberculosis: a guide for low income countries. 5th ed. 2000. www.iuatld.org.

  9. www.worldbank.org/mx. Página consultada el 1 de septiembre, 2005.

  10. Peter CR, Schultz E, Moser K, et al. Drug-resistant tuberculosis in the Baja California-San Diego County border population. West J Med 1998;169:208-213.

  11. Centers for Disease Control and Prevention. Population-based survey for drug resistance of tuberculosis-Mexico 1997. MMWR 1998;47:371-375.

  12. Laniado-Laborín R, Cabrales-Vargas N. Tratamiento acortado estrictamente supervisado: estrategia necesaria pero no suficiente para controlar la tuberculosis en Baja California, México. Elevadas tasas de resistencia en el estado. Rev Inst Nal Enf Resp Mex 2000;13:23-27.

  13. Garcia-Garcia ML, Ponce de Leon A, Jiménez-Corona ME, et al. Clinical consequences and transmissibility of drug-resistant tuberculosis in southern Mexico. Arch Intern Med 2000;160:630-636.




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Rev Inst Nal Enf Resp Mex. 2005;18