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2014, Number 1

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Gac Med Mex 2014; 150 (1)

Efficacy and adverse effects of oral antidiabetic agents

Zárate A, Islas S, Saucedo R
Full text How to cite this article

Language: Spanish
References: 9
Page: 5-7
PDF size: 203.16 Kb.


Key words:

Diabetes, Oral antidiabetics, Adverse effects.

ABSTRACT

The management of type 2 diabetes is still a challenge and a conundrum for treatment intensity and choice of pharmaceutical agent. There is also uncertainty about possible cardiovascular adverse effects.


REFERENCES

  1. Lebovitz HE. Keeping tabs on oral agents. Diabetes Care. 1988;11: 598-9.

  2. Hemmingsen B, Lund SS, Wetterslev J, Vaag A. Oral hypoglycaemic agents, insulin resistance and cardiovascular disease in patients with type 2 diabetes. Eur J Endocrinol. 2009;161:1-9.

  3. Zárate A, Basurto L, Saucedo R, Hernández-Valencia M. Guía para seleccionar el tratamiento farmacológico en diabetes 2. Rev Med Inst Mex Seguro Soc. 2010;48:293-6.

  4. The ACCORD Study Group. Long-term effects of intensive glucose lowering on cardiovascular outcomes. N Engl J Med. 2011;364: 818-28.

  5. European Association for the Study of Diabetes Congress 2013 Barcelona. [Internet] Disponible en: www.diabetes-symposium.org.

  6. Nissen SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med. 2007;356:2457-71.

  7. Home PD, Pocock SJ, Beck-Nielsen H. Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomized, open-label trial. Lancet. 2009;373:2125-35.

  8. Hiatt WR, Kaul S, Smith RJ. The cardiovascular safety of diabetes drugs-insights from the rosiglitazone experience. N Engl J Med. 2013; 369:1285-7.

  9. Scirica BM, Bhatt DL, Braunwald E, Steg G, Davidson J, Hirshberg B. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med. 2013;369:1317-26.




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C?MO CITAR (Vancouver)

Gac Med Mex. 2014;150