Cedré HT, Martínez CL, García CMB

Language: Spanish
References: 10
Page:
PDF size: 32.23 Kb.

ABSTRACT

Acute lymphoblastic leukaemia represents 80% of all the cases of infantile leukaemias and it is one of the first malignant disease in those that therapeutic clinical studies have been made to great scale. With the improvement of the therapeutic outlines the prognosis of the children with acute lymphoblastic leukaemia has improved considerably in the last four decades, with rates of survival to the five years higher than 80%. The achievements in the “José Luis Miranda” Pediatric Hospital in Villa Clara is located at the level of national and internationally informed, with 84% of survival at five years and 16.5% of relapses; they are also informed late adverse effects.

REFERENCES

1. Whitlock JA, Gaynon PS. Acute lymphoblastic leukaemia in children. En: Greer JP, Foerster J, Lukens JN, Rodgers GN. Wintrobe Clinical Hematology. 12mo ed. Philadelphia: Lippincott Williams & Wilkins Publishers; 2009. p. 654-58.

2. Schrappe M, Nachman J, Hunger S, Schmiegelow K, Conter V, Masera G, et al. Educational symposium on long-term results of large prospective clinical trials for childhood acute lymphoblastic leukemia (1985–2000). Leukemia [Internet]. 2010 [citado 12 Feb 2012];24:[aprox. 10 p.]. Disponible en: http://hinarigwwho.int/whalecomwww.nature.com/whalecom0/leu/journal/v24/n2/ful l/leu2009250a.html

3. National Cancer Institute. SEER cancer statistics review 1975-2008 [Internet]. SEER data submission, posted to the SEER web site; 2011 [citado 12 Feb 2012]. Disponible en: http://www.seer.cancer.gov/csr/1975_2008/

4. Vergara B, Cedré T, Martínez L, López C, González F, Pich V. Supervivencia y calidad de vida de pacientes con leucemia linfoide aguda. Resultados del Hospital Pediátrico “José Luis Miranda” (1969-2003). Rev Cubana Pediatr [Internet]. 2005 [citado 12 Feb 2012];77(3-4):[aprox. 3 p.]. Disponible en: http://bvs.sld.cu/revistas/ped/vol77-3-04/pedsu304.htm

5. Vergara B, Svarch E, González A, Machín S, Campos M, González F, et al. Leucemia linfoblástica aguda infantil. Seguimiento post-finalización del tratamiento en 430 pacientes. Rev Esp Pediatr. 2004;60(5):348-55.

6. Trigg M, Sather H, Reaman G, Tubergen D, Steinherz P, Gaynon P, et al. Ten-year survival of children with acute lymphoblastic leukemia: A report from the Children’s Oncology Group. Leuk Lymphoma. 2008 Jun;49(6):1142-54. doi: 10.1080/10428190802074593

7. Tsurusawa M, Shimomura Y, Asami K, Kikuta A, Watanabe A, Horikoshi Y. Long-term results of the Japanese Childhood Cancer and Leukemia Study Group studies 811, 841, 874 y 911 on childhood acute lymphoblastic leukemia. Leukemia [Internet]. 2010 [citado 4 May 2013];24(2): [aprox. 6 p.]. Disponible en: http://hinarigw.who.int/whalecomwww.nature.com/whalecom0/leu/journal/v24/n2/fu ll/leu2009259a.html

8. Silverman LB, Stevenson KE, O’Brien JE, Asselin BL, Barr RD, Clavell L, et al. Longterm results of DFCI ALL Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1985-2000). Leukemia [Internet]. 2010 [citado 4 May 2013];24: [aprox. 15 p.]. Disponible en: http://hinarigw.who.int/whalecomwww.nature.com/whalecom0/leu/journal/v24/n2/fu ll/leu2009253a.html

9. Schmiegelow K, Forestier E, Hellebostad M, Heyman M, Kristinsson J, Soderhall S. Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia. Leukemia [Internet]. 2010 [citado 12 Feb 2012];24(2): [aprox. 10 p.]. Disponible en: http://hinarigw.who.int/whalecomwww.nature.com/whalecom0/leu/journal/v24/n2/fu ll/leu2009251a.html

10. Shah A, Stiller CA, Kenward MG, Vincent T, Eden TO, Coleman MP. Childhood leukemia: long-term excess mortality and the proportion “cured”. Br J Cancer [Internet]. 2008 [citado 12 Feb 2012];99(1): [aprox. 15 p.]. Disponible en: http://hinarigw.who.int/whalecomwww.nature.com/whalecom0/bjc/journal/v99/n1/fu ll/6604417a.html