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Órgano Oficial de la Asociación Dental Mexicana

2005, Number 5

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Rev ADM 2005; 62 (5)

Changes in laminin expression in periodontal ligament from teeth subject to orthodontic pressure in humans

Gutiérrez SJ, Morales GJA, Vargas CLD, Marichi RF, Esquivel SJ

Language: Spanish
References: 18
Page: 171-176
PDF size: 116.76 Kb.


ABSTRACT

Objective: The objective of this study was to determine presence of laminin, in the periodontal ligament (PL) from premolars to those that were applied orthodontic forces. Hypothesis: Laminin from the periodontal ligament of teeth subject to orthodontic pressure will present modifications in its expression. Design, material and methods: Orthodontic forces was placed clinically in healthy subjects in its first superior premolars being the right experimental (with orthodontic force application) and the left one the control (without orthodontic force application). After three weeks, the PL was obtained to determine the presence of laminin by means of Western-blot technique. Results: The results showed that, in comparison of the premolars that were not subjected to orthodontic forces; those that if they had orthodontic forces they presented a decrease statistically significant in the laminin presence. Conclusions: Our results indicate that changes exist at molecular level in the PL of teeth that were subjected to orthodontic forces.


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