medigraphic.com
SPANISH

Revista de Especialidades Médico-Quirúrgicas

Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2014, Number 1

<< Back Next >>

Rev Esp Med Quir 2014; 19 (1)

Circulating tumor cells in breast cancer: a potential biological hazard

Morán ME, Rodríguez GJ, Lara LM, Piña LC, Thompson BMR, Rosas SG, Moreno SHN, Calderón RMG, Rangel GSI, Merino GJL, González BJA
Full text How to cite this article

Language: Spanish
References: 22
Page: 45-51
PDF size: 718.07 Kb.


Key words:

CTCs, Breast cancer, Molecular diagnosis, Blood transfusion.

ABSTRACT

At the present time, cancer affects millions of persons worldwide. Due to this fact, research in this area is thorough. Nevertheless, there are many voids in knowledge. Today it is known that from early stages, a neoplastic process can deliver cells to the bloodstream that have similar characteristics to the tumor cells (Circulating Tumor Cells, CTCs). Given certain condition, these cells can anchor to almost any tissue different to the original and generate a new tumor growth (metastasis). The purpose of this revision is to describe the behavior, identification and clinical relevancy in diagnosis and prognosis of these cells, as well as a risk agent in transfusion therapy.


REFERENCES

  1. OMS | Cáncer [Internet]. WHO. Disponible en: http://www. who.int/topics/cancer/es/

  2. Knaul F, López-Carillo L, et al. México Reporte Rosa 2009- 2010: Cáncer de mama a conciencia. Informe final. Primera edición. México, DF: Fundación Mexicana para la Salud; 2009.

  3. OMS | Cáncer de mama: prevención y control [Internet]. WHO. Disponible en: http://www.who.int/topics/cancer/ breastcancer/es/index.html

  4. Circulating Tumor Cells for Cancer Diagnosis and Prognosis - Circulating Tumor Cells for Cancer Diagnosis and Prognosis. Disponible en: http://cancer.scripps.edu/research. aspx

  5. Ribatti D, Mangialardi G, Vacca A. Stephen Paget and the “seed and soil” theory of metastatic dissemination. Clin ExperMed. 2006;6:145–9.

  6. Graves H, Czerniecki BJ. Circulating Tumor Cells in Breast Cancer Patients: An Evolving Role in Patient Prognosis and Disease Progression. Pathology Research International, 2011.

  7. Kim SI, Jung H. Circulating Tumor Cells: Detection Methods and Potential Clinical Application in Breast Cancer. Journal of Breast Cancer 2010;13:125.

  8. Alix-Panabières C, Riethdorf S, Pantel K. Circulating Tumor Cells and Bone Marrow Micrometastasis. Clin Cancer Res 2008;14:5013–21.

  9. Ross JS, Slodkowska EA. Circulating and Disseminated Tumor Cells in the Management of Breast Cancer. AJCP 2009;132:237–45.

  10. Hou J-M, Krebs M, Ward T, Morris K, Sloane R, Blackhall F, et al. Circulating Tumor Cells, Enumeration and Beyond. Cancers 2010;2:1236–50.

  11. How does the CELLSEARCH® CTC Test work? Disponible en: https://www.cellsearchctc.com/about-cellsearch/ how-cellsearch-ctc-test-works

  12. Sieuwerts AM, Kraan J, Bolt J, et al. Anti–epithelial cell adhesion molecule antibodies and the detection of circulating normal-like breast tumor cells. J Natl Cancer Inst 2009;101:61-66.

  13. Clinical Studies. Disponible en: http://www.adnagen. com/cfscripts/main_technology_clinical_studies. cfm?auswahl=01.25.20

  14. Dotan E, Cohen SJ, Alpaugh KR, Meropol NJ. Circulating Tumor Cells: Evolving Evidence and Future Challenges. The Oncologist 2009;14:1070–82.

  15. Ebeed SA, El-Moneim A, A N, Saad A, Zaher ER, Yassin OG, et al. Diagnostic and prognostic value of circulating tumor cells in female breast cancer patients. Alexandria Journal of Medicine 2012;48:197–206.

  16. Tanaka F, Yoneda K, Kondo N, Hashimoto M, Takuwa T, Matsumoto S, et al. Circulating Tumor Cell as a Diagnostic Marker in Primary Lung Cancer. Clin Cancer Res 2009;15:6980–6.

  17. Nolé F, Munzone E, Zorzino L, Minchella I, Salvatici M, Botteri E, et al. Variation of circulating tumor cell levels during treatment of metastatic breast cancer: prognostic and therapeutic implications. Ann Oncol 2008;19:891–7.

  18. Iakovlev VV, Goswami RS, Vecchiarelli J, Arneson NCR, Done SJ. Quantitative detection of circulating epithelial cells by Q-RT-PCR. Breast Cancer Research and Treatment. 2007;107:145–54.

  19. Dawood S, Broglio K, Valero V, Reuben J, Handy B, Islam R, et al. Circulating tumor cells in metastatic breast cancer: from prognostic stratification to modification of the staging system? Cancer 2008;113:2422–30.

  20. Riethdorf S, Fritsche H, Müller V, Rau T, Schindlbeck C, Rack B, et al. Detection of Circulating Tumor Cells in Peripheral Blood of Patients with Metastatic Breast Cancer: A Validation Study of the CellSearch System. Clin Cancer Res 2007;13:920–8.

  21. Sieuwerts AM, Kraan J, Bolt J, Spoel P van der, Elstrodt F, Schutte M, et al. Anti-Epithelial Cell Adhesion Molecule Antibodies and the Detection of Circulating Normal-Like Breast Tumor Cells. JNCI J Natl Cancer Inst 2009;101:61–6.

  22. Ren C, Han C, Wang D, Zhao X, Jin G, Shen H. Detection of circulating tumor cells: Clinical relevance of a novel metastatic tumor marker. Exp Ther Med 2011;2:385–91.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev Esp Med Quir. 2014;19