medigraphic.com
SPANISH

Acta Pediátrica de México

Órgano Oficial del Instituto Nacional de Pediatría
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2014, Number 2

<< Back Next >>

Acta Pediatr Mex 2014; 35 (2)

Concurrent measurement of total transcutaneous bilirubin over forehead and sternum as predictive model for total serum bilirubin in premature and term newborns

Martínez-Mercado ME, Torres-Bernal LF, Góngora-Ortega J, Sánchez-Ortiz MR, Guerrero-Díaz de León JA
Full text How to cite this article

Language: Spanish
References: 15
Page: 118-124
PDF size: 424.02 Kb.


Key words:

Transcutaneous bilirubin, bilirubinometer, neonatal hyperbilirubinemia, kernicterus.

ABSTRACT

Background. Detection of hyperbilirubinemia in newborn has become a challenge for health care systems. The aim of the study was to prove the usefulness of concurrent total transcutaneous bilirubin measurement over forehead (TTBf) and total transcutaneous bilirubin over sternum (TTBs) as predictive model for total serum bilirubin (TSB) in premature and term newborns.
Material and Method. Transversal and analytical study in 30-42 gestation week newborns from January 21st to April 30th 2013 in a gynecology, obstetrics and neonatology specialties public hospital. Pearson´s correlation for TSB/TTBf and TSB/TTBs was carried out. Linear regression analysis for one and several predictive variables were performed.
Results. For 89 concurrent measurements, the correlation TSB/TTBf was 0.8411 and for TSB/TTBs, 0.7942 (p value ‹ 2.2E-16 in both cases). With simple regression analysis for TSB and TTBf, the equation was: TSB = 2.1187 + 0.7035 × TTBf (p ‹ 2.2E-16, R2 = 70.75%, R2 adjusted = 70.41%); for TSB and TTBs the equation was: TSB = 2.0405 + 0.6349 × TTBs (p ‹ 2.2E-16, R2 = 63.07%, R2 adjusted = 62.65%). With multiple regression analysis for TSB vs. TTBf, TTBs, the equation was: BTS = 1.620 + 0.503 × TTBf + 0.224 × TTBs (p ‹ 2.2 E-16, R2 = 72.87%, R2 adjusted = 72.24%).
Conclusions. It was demonstrated that TTBf, TTBs model allowed to obtain better TSB prediction than TTB single measurement models for in-patient premature and term newborns.


REFERENCES

  1. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics 2004;114:297- 316.

  2. Maisels MJ, Bhutani VK, Bogen D, Newman TB, Stark AR, Matchko JF. Hyperbilirubinemia in the newborn infant 35 weeks gestation: an update with clarifications. Pediatrics 2009;124:1193-98.

  3. Jiménez B, Miguel MA, Acosta JM, Fernández MP. Detección no invasiva de hiperbilirrubinemia: evaluación clínica y bilirrubina transcutánea con bilirrubina sérica. Rev Sanid Milit Mex 2010;64:54-60.

  4. Rubaltelli FF, Gourley GR, Loskamp N, Modi N, Roth-Kleiner M, Sender A, Vert P. Transcutaneous Bilirubin Meassurement: A Multicenter Evaluation of a New Device. Pediatrics 2001;107:1264-71.

  5. Bhutani BK, Gourly GR, Adler S, Kreamer B, Dalin Ch, Johnson LH. Noninvasive Measurement of Total Serum Bilirubin in a Multiracial Predischarge Newborn Population to Assess the Risk of Severe Hyperbilirubinemia. Pediatrics 2000;106;e17.

  6. Romagnoli C, Tiberi E, Barone G, De Curtis M, Regoli D, Paolillo P, et al. Validation of transcutaneous bilirubin nomogram in identifying neonates not at risk of hyperbilirubinaemia: A prospective, observational, multicenter study. Early Hum Dev 2012;88:51-5.

  7. Jangaard KA, Curtis H, Goldbloom RB, Hon D. Estimation of bilirubin using BiliChekTM, a transcutaneous bilirubin measurement device: Effects of gestational age and use of phototherapy. Paediatr Child Health 2006;11:79-83.

  8. Fouzas S, Mantagou L, Skylogianni E, Mantagos S, Varvarigou A. Transcutaneous Bilirubin Levels for the First 120 Postnatal Hours in Healthy Neonates. Pediatrics 2010;125; e52.

  9. Holland L, Blick K. Implementing and Validating Transcutaneous Bilirubinometry for Neonates. Am J Clin Pathol 2009;132:555-61.

  10. Poland RL, Hartenberger C, McHenry H, Hsi A. Comparison of Skin for Sites for Estimating Serum Total Bilirubin in In- Patientes and Out-Patients: Chest is Superior to Brow. J Perinatol 2004;24:541-3.

  11. Ho E, Lee S, Chow C, Chung J. Bilicheck transcutaneous bilirubinometer: a screening tool for neonatal jaundice in the Chinese population. Hong Kong Med J 2006;12:99-102.

  12. Stillova L, Matasova K, Mikitova T, Stilla J, Kolarovszka H, Zibolen M. Evaluation of Transcutaneous Bilirubinometry in Preterm Infants of Gestational Age 32-34 Weeks. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2007;151:267-71.

  13. Rodríguez-Weber MA, López-Candiani C, Valencia-Salazar G, Millote-Galindo G. Eficacia de un analizador de bilirrubina no invasivo en neonatos. Bol Med Hosp Infant Mex 1999;56:539-42.

  14. Draper NR, Smith H. Applied Regression Analysis. 3th edition. USA. Wiley Series in Probability and Statistics, 1998, pp. 327-68.

  15. Engle WD, Jackson GL, Dendelbach D, Manning D, Frawley WH. Assessment of a Transcutaneous Device in the Evaluation of Neonatal Hyperbilirubinemia in a Primarly Hispanic Population. Pediatrics 2002;110:61-7.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Acta Pediatr Mex. 2014;35