2014, Number 3
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ABSTRACTSince the first results from the Framingham Heart Study, the medical community has gained interest in the risk factors for developing cardiovascular diseases, because there is evidence of the coexistence of conditions. The metabolic syndrome officially appeared in 1988, when Gerald Reaven described “syndrome X” as the association of insulin resistance/ hyperinsulinemia (dysglycemia), dyslipidemia and hypertension and his new entity got its name by WHO in 1999. In fact, the association of this cardiovascular risk factors is known since ancient times and, through history, has been given many names, such as “hypertensionhyperglycemia- hyperuricemia syndrome”, “plurimetabolic syndrome”, “diabetogenic obesity”, etc. Numerous international organizations have sought to establish operational definitions, modifying the importance and/or the cutoff values for certain variables. This paper describes the historical background and scientific advances that allowed establishing the syndrome, as well as the different operating variables and definitions that have been used to diagnose it.
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