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2014, Number 1

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Enf Infec Microbiol 2014; 34 (1)

Bilateral adrenal histoplasmosis: case report and literature review

Vargas GLF, Ramírez RA, De Leija GMA, Ayala-Gaytán JJ

Language: Spanish
References: 14
Page: 37-42
PDF size: 221.67 Kb.


ABSTRACT

Histoplasmosis is an infection caused by inhaling spores of a dimorphic fungus called Histoplasma capsulatum. The soil rich in bird and bat droppings is their natural habitat, in which it exists in its mycelial form. The disease is endemic in the United States, Central and South America as well as Africa and Asia. The clinical presentation of histoplasmosis ranges from asymptomatic or self-limited to progressive widespread disease that could endanger life. The affection of adrenal glands is uncommon, however immunocompromised patients with impaired cellular immunity mainly are the most likely to have this form of disseminated infection. There are several methods for its diagnosis, detection of urinary H. capsulatum antigen and serological tests are those with major use in disseminated histoplasmosis suspected; however, diagnosis would be confirmed by presence of typical H. capsulatum yeast on the biopsy. The choice of treatment, doses and duration depend on the clinical presentation, pre-existing factors, complications and patient’s immune status. We report of a case and literature review.


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