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2005, Number 3

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Med Sur 2005; 12 (3)

Hepatitis because of Epstein-Barr virus:
A case report

Hernández-Estrada S, Aguilar DC, Lizardi CJ

Language: Spanish
References: 12
Page: 177-179
PDF size: 47.79 Kb.


ABSTRACT

Epstein-Barr Virus is the causative agent of infectious mononucleosis. The common manifestations are fever, pharyngitis, limphadenopathy, hepatosplenomegaly and atypical lymphocytosis. Infectious mononucleosis is caused by an intense cytotoxic T lymphocyte response to eliminate EBV-infected B cells. Rarely, it results in hepatic injury with severe jaundice. The histological features are characterized by a mild increase in portal inflammation that consists of lymphocytes. In this case Epstein-Barr Virus did not infect hepatocytes, but infected T cells.


REFERENCES

  1. Godshall A. Infectious mononucleosis: Complexities of a common syndrome. Posgrad Med 2000; 107: 175.

  2. Crawford DH. Epstein-Barr Virus. Recent Advances. The Lancet Infect Dis 2003; 3: 131-40.

  3. Borer A. Clinical features and costs of care for hospitalized adults with primary EBV infection. Am J Med 1999; 107: 144.

  4. Kinoshita E. Persistent hepatitis associated with chronic active Epstein-Barr Virus Infection. Pediatr Infect Dis 2004; 23: 74-6.

  5. Hara S. Association of virus infected-T cell in severe Hepatitis caused by primary Epstein-Barr virus Infection. Jour of Clin Virol 2005: 1-7.

  6. Feranchak A. Fulminant Epstein-Barr Viral Hepatitis. Orthotopic liver transplantation and review of the literature. Liver Trans 4, 1998: 469-76.

  7. Balfour H. A Prospective Clinical Study of Epstein-Barr Virus and Host Interactions during Acute Infectious Mononucleosis. 2005; 192: 1502-12.

  8. Kimura H. Differences between T cell-type and natural killer cell-type chronic active Epstein-Barr virus Infection. J Infect Dis 2005; 191: 531-9.

  9. Woodberry,T. Differential Targeting and Shifts in the Immunodominance of Epstein-Barr Virus Specific CD8 and CD4 Cell responses during Acute Persistent Infection. 2005; 192: 1513-24.

  10. Kimura H. Severe Hepatitis caused by Epstein-Barr Virus without infection of hepatocytes. Hum Pathol 2001; 32: 757-62.

  11. Temak G. Epstein-Barr Virus Reactivation. Lancet Infect Dis 2003; 3: 271.

  12. Mendez-Sanchez N, Aguilar C. Hepatic manifestations of Epstein-Barr viral infection. Ann Hepatol 2005; 4(3): 205-9.




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